183742-33-8

• 常用中文名：N-4-BOC-2-哌嗪乙酸 甲基 酯
• 常用英文名：Methyl 4-Boc-piperazine-2-acetate
• CAS号：183742-33-8
• 分子式：C₁₂H₂₂N₂O₄
• 分子量：258.314
• 发布时间：2018-12-27 17:38:05
• 更新时间：2024-01-02 18:45:16
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名称

• 中文名: N-4-BOC-2-哌嗪乙酸甲酯
• 英文名: tert-butyl 3-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate
• 中文别名: N-4-Boc-2-哌嗪乙酸甲酯; N-4-叔丁氧羰基-2-哌嗪乙酸甲酯; N-4-BOC-2-哌嗪乙酸 甲基 酯; N-4-BOC哌嗪-2-乙酸甲酯; 4-BOC-哌嗪-2-乙酸乙酯
• 英文别名: N-4-Boc-2-piperizineacetic acid methyl ester; tert-butyl 3-(2-methoxy-2-oxoethyl) piperazine-1-carboxylate; methyl 4-[(1,1-dimethylethoxy)carbonyl]-2-piperazineacetate; 3-methoxycarbonylmethyl-piperazine-1-carboxylic acid tert-butyl ester; methyl 2-{4-[(tert-butyl)oxycarbonyl]piperazin-2-yl}acetate; N-4-BOC-2-PIPERAZINEACETIC ACID METHYL ESTER; 4-(tert-butoxycarbonyl)piperazin-2-ylacetic acid methyl ester; 2-Methyl-2-propanyl 3-(2-methoxy-2-oxoethyl)-1-piperazinecarboxylate; tert-butyl 3-(2-methoxy-2-oxoethyl)piperazine-1-ncarboxylate; 2-Piperazineacetic acid, 4-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; MFCD01861213; tert-butyl 3-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate; Methyl 4-Boc-piperazine-2-acetate

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 336.2±17.0 °C at 760 mmHg
• 分子式: C₁₂H₂₂N₂O₄
• 分子量: 258.314
• 闪点: 157.1±20.9 °C
• 精确质量: 258.157959
• PSA: 67.87000
• LogP: 0.71
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.465

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933599090

合成路线

314741-49-6 ~% 183742-33-8

文献：EP1187828 B1, ; Page 15 ;

183742-32-7 74651-77-7 ~% 183742-33-8

文献：US6432947 B1, ;

183742-32-7 ~% 183742-33-8

文献：Journal of Medicinal Chemistry, , vol. 50, # 6 p. 1146 - 1157

368441-98-9 58632-95-4 ~% 183742-33-8

文献：Davey, David D.; Adler, Marc; Arnaiz, Damian; Eagen, Keith; Erickson, Shawn; Guilford, William; Kenrick, Margaret; Morrissey, Michael M.; Ohlmeyer, Mike; Pan, Gonghua; Paradkar, Vidyadhar M.; Parkinson, John; Polokoff, Mark; Saionz, Kurt; Santos, Cecile; Subramanyam, Babu; Vergona, Ron; Wei, Robert G.; Whitlow, Marc; Ye, Bin; Zhao, Zuchun; Devlin, James J.; Phillips, Gary Journal of Medicinal Chemistry, 2007 , vol. 50, # 6 p. 1146 - 1157

1117-71-1 ~% 183742-33-8

文献：US2011/288069 A1, ;

上下游产品

上游产品  6
314741-49-6 183742-32-7 74651-77-7 368441-98-9
58632-95-4 1117-71-1
下游产品  1
1188265-73-7

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%