18968-99-5

• 常用中文名：PEMOLINE 镁
• 常用英文名：MAGNESIUM PEMOLINE
• CAS号：18968-99-5
• 分子式：C₉H₁₀MgN₂O₄
• 分子量：234.49200
• 发布时间：2018-09-12 15:16:35
• 更新时间：2024-01-11 11:46:16

名称

• 中文名: PEMOLINE 镁
• 英文名: magnesium,2-amino-5-phenyl-1,3-oxazol-4-one,dihydroxide
• 英文别名: Pemoline magnesium chelate; 2-Amino-5-phenyl-2-oxazolin-4-one + Mg(OH)2; Magnesium pemoline; Pemoline magnesium; Pemoline magnesium hydroxide mixture; Tamilan; Pemoline magnesium hydroxide; Pemolin and magnesium hydroxide; DEA No. 1530

物化性质

• 沸点: 313.6ºC at 760 mmHg
• 分子式: C₉H₁₀MgN₂O₄
• 分子量: 234.49200
• 闪点: 143.4ºC
• 精确质量: 234.04900
• PSA: 105.14000
• LogP: 0.38150

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RY1105000 CHEMICAL NAME : Pemoline magnesium CAS REGISTRY NUMBER : 18968-99-5 LAST UPDATED : 199712 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C9-H10-Mg-N2-O4 MOLECULAR WEIGHT : 234.52 WISWESSER LINE NOTATION : T5OYMV EHJ BUM ER &-MG- HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - child DOSE/DURATION : 149 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Gastrointestinal - nausea or vomiting REFERENCE : CPEDAM Clinical Pediatrics (Philadelphia). (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1962- Volume(issue)/page/year: 18,761,1979 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 485 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,810,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - irritability Lungs, Thorax, or Respiration - other changes REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 181,441,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 487 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 181,441,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Primate - monkey DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - changes in motor activity (specific assay) Skin and Appendages - hair REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 181,441,1969