68672-66-2

• 常用中文名：(Z)-2-(2-三苯甲基氨基噻唑-4-基)-2-(2-叔丁氧羰基丙-2-氧亚氨)乙酸
• 常用英文名：(Z)-2-(2-Tritylaminothiazol-4-yl)-2-(2-tert-butoxycarbonylprop-2-oxyimino)acetic acid
• CAS号：68672-66-2
• 分子式：C₃₂H₃₃N₃O₅S
• 分子量：571.68700
• 发布时间：2019-01-10 12:34:15
• 更新时间：2026-07-14 17:50:20

名称

• 中文名: (Z)-2-(2-三苯甲基氨基噻唑-4-基)-2-(2-叔丁氧羰基丙-2-氧亚氨)乙酸
• 英文名: (Z)-2-(tert-Butoxycarbonylprop-2-oxyimino)-2-(2-tritylaminothiazol-4-yl)acetic acid
• 中文别名: 三苯甲烷基他定侧链酸; 三苯甲烷基他啶侧链酸
• 英文别名: (Z)-2-(((1-(tert-Butoxy)-2-methyl-1-oxopropan-2-yl)oxy)imino)-2-(2-(tritylamino)thiazol-4-yl)acetic acid; (Z)-2-(2-Tritylaminothiazol-4-yl)-2-(2-tert-butoxycbonylprop-2-oxyimino)acetic acid; (Z)-alpha-[[2-(tert-butoxy)-1,1-dimethyl-2-oxoethoxy]imino]-2-(tritylamino)thiazol-4-acetic acid; (αZ)-α-[[2-(1,1-Dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-2-[(triphenylmethyl)amino]-4-thiazoleacetic acid; MFCD08703305; (Z)-2-(tert-Butoxycbonylprop-2-Oxyimino)-2-(2-Tritylamino; (Z)-2-(2-TRITYLAMINOTHIAZOL-4-YL)-2-(1-T-BUTOXYCBONYL-1-METHYL)ETHOXYIMINOACETICACID; (Z)-2-(2-tritylaminothiazol-4-yl)-2-(2-t-butoxycbonylprop-2-oxyimino)-acetic a; 4-Thiazoleacetic acid, α-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-2-[(triphenylmethyl)amino]-, (αZ); TB-TAA:(Z)-2-(TERT-BUTOXYCBONYLPROP-2-OXYIMINO)-2-(2- TRITYLAMINOTHIAZOL-4-YL) ACETIC ACID; EINECS 272-056-6; (Z)-2-(Tert-butoxycbonylprop; Z-2-(t-Boc-prop-2-oxyimino)-2-(2-tritylamino-thiazol-4-yl)aceticacid=TB-TAA; tb-taa; TB-TAA; (Z)-α-[[2-(tert-butoxy)-1,1-dimethyl-2-oxoethoxy]imino]-2-(tritylamino)thiazol-4-acetic acid; (Z)-2-(TERT-BUTOXYCBONYLPROP-2-OXYIMINO)-2-(2-TRITYLAMINO-THIAZOL-4-YL)ACETIC ACID

物化性质

• 密度: 1.19 g/cm3
• 沸点: 707.5ºC at 760 mmHg
• 分子式: C₃₂H₃₃N₃O₅S
• 分子量: 571.68700
• 闪点: 381.7ºC
• 精确质量: 571.21400
• PSA: 138.35000
• LogP: 6.54570
• 外观性状: 白色至灰白色结晶粉末
• 折射率: 1.597

合成路线

76-83-5 86299-47-0 ~89% 68672-66-2

文献：NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD.; BURNS, Christopher, J.; GOSWAMI, Rajesh; JACKSON, Randy, W.; LESSEN, Thomas; LI, Weiping; PEVEAR, Daniel; TIRUNAHARI, Pavan, Kumar; XU, Hongyu Patent: WO2010/130708 A1, 2010 ; Location in patent: Page/Page column 108 ; WO 2010/130708 A1

76-83-5 ~% 68672-66-2

文献：US6214997 B1, ;

68672-65-1 ~61% 68672-66-2

文献：Bucourt; Heymes; Perronnet; et al. European Journal of Medicinal Chemistry, 1981 , vol. 16, # 4 p. 307 - 316

23877-12-5 ~% 68672-66-2

文献：European Journal of Medicinal Chemistry, , vol. 16, # 4 p. 307 - 316

66339-00-2 ~% 68672-66-2

文献：European Journal of Medicinal Chemistry, , vol. 16, # 4 p. 307 - 316

66338-99-6 ~% 68672-66-2

文献：Journal of Heterocyclic Chemistry, , vol. 21, # 4 p. 1097 - 1111

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