28543-07-9

• 常用中文名：茶黄素 3'-没食子酸酯
• 常用英文名：Theaflavin-3'-gallate
• CAS号：28543-07-9
• 分子式：C₃₆H₃₂O₁₅
• 分子量：704.630
• 相关类别： 生物化工 中草药成分
• 发布时间：2018-02-25 08:00:00
• 更新时间：2026-07-03 11:59:59
• Theaflavin-3'-gallate 是一种红茶茶黄素单体,被认为是红茶生物学上重要的活性成分,有益健康。Theaflavin-3'-gallate 充当促氧化剂并在癌细胞中诱导氧化应激。Theaflavin-3'-gallate 可以以时间和浓度依赖性方式与还原型谷胱甘肽 (GSH) 直接反应。

名称

• 中文名: 茶黄素-3-没食子酸酯
• 英文名: theaflavin 3'-o-gallate
• 中文别名: 茶黄素-3'-没食子酸酯; 茶黄素-3'-没食子酸酯对照品; (2R,3R)-5,7-二羟基-2-(3,4,6-三羟基-5-氧代-8-((2R,3R)-3,5,7-三羟基苯并二氢吡喃-2-基)-5H-苯并环庚烯-1-基)苯并二氢吡喃-3-基 3,4,5-三羟基苯甲酸酯; 茶黄素3'-没食子酸; 茶黄素-3'-没食子酸酯(标准品); 茶黄素-3'-没食子酸酯(TF-3'-G); 茶黄素的3-没食子酸酯
• 英文别名: THEAFLAVIN 3'-O-GALLATE; theaflavin-3-gallate; Theaflavine 3-O-gallate; Theaflavin3'Gallate,inhibit,Inhibitor,Theaflavin 3' Gallate; Theaflavin-3''-Gallate; THEAFLAVIN3GALLATE(3'-ISOMERICFORM); Theaflavin-3'-Gallate (TF-3'-G); 3,4,5-Trihydroxybenzoic acid (2R,3R)-2-[8-[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-5-oxo-5H-benzocyclohten-1-yl]-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester; Theaflavin 2B; theaflavin-3-O-gallate; Theaflavin 3'-gallate; Theaflavin-3’-gallate; 3'-O-(3,4,5-Trihydroxybenzoyl); THEAFLAVINMONOGALLATEB; Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-2-[(6R)-4-[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-6,7,8,9-tetrahydro-1,2-dihydroxy-9-oxo-5H-benzocyclohepten-6-yl]-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester; [(2S,3R)-5,7-dihydroxy-2-[6,8,9-trihydroxy-5-oxo-3-[(2S,3R)-3,5,7-trihydroxychroman-2-yl]-11-bicyclo[5.4.0]undeca-1,3,6,8,10-pentaenyl]chroman-3-yl] 3,4,5-trihydroxybenzoate; TF-3'-G; (2R,3R)-5,7-Dihydroxy-2-(3,4,6-trihydroxy-5-oxo-8-((2R,3R)-3,5,7-trihydroxychroman-2-yl)-5H-benzoannulen-1-yl)chroman-3-yl 3,4,5-trihydroxybenzoate; (2R,3R)-2-{(6R)-1,2-Dihydroxy-9-oxo-4-[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]-6,7,8,9-tetrahydro-5H-benzo[7]annulen-6-yl}-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate; Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-2-[8-[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-5-oxo-5H-benzocyclohten-1-yl]-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester; THEAFLAVIN 3'-O-GALLATE //BP

物化性质

• 密度: 1.8±0.1 g/cm3
• 沸点: 1135.6±65.0 °C at 760 mmHg
• 分子式: C₃₆H₃₂O₁₅
• 分子量: 704.630
• 闪点: 361.0±27.8 °C
• 精确质量: 704.174133
• PSA: 264.13000
• LogP: 4.61
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.836
• 储存条件: 2-8℃

生物活性

• 描述: Theaflavin-3'-gallate 是一种红茶茶黄素单体,被认为是红茶生物学上重要的活性成分,有益健康。Theaflavin-3'-gallate 充当促氧化剂并在癌细胞中诱导氧化应激。Theaflavin-3'-gallate 可以以时间和浓度依赖性方式与还原型谷胱甘肽 (GSH) 直接反应。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Babich H, et al. Theaflavin-3-gallate and theaflavin-3'-gallate, polyphenols in black tea with prooxidant properties. Basic Clin Pharmacol Toxicol. 2008 Jul;103(1):66-74.

安全

• 海关编码: 29182900

合成路线

1257-08-5 970-74-1 ~% 28543-07-9

文献：Sang, Shengmin; Lambert, Joshua D.; Tian, Shiying; Hong, Jungil; Hou, Zhe; Ryu, Jae-He; Stark, Ruth E.; Rosen, Robert T.; Huang, Mou-Tuan; Yang, Chung S.; Ho, Chi-Tang Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 2 p. 459 - 467

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