37439-34-2

• 常用中文名：三氯吡啶醇钠
• 常用英文名：Sodium 3,5,6-trichloro-2-pyridinolate
• CAS号：37439-34-2
• 分子式：C₅HCl₃NNaO
• 分子量：220.416
• 相关类别： 化学农药原药 杀虫剂中间体
• 发布时间：2018-12-05 16:13:12
• 更新时间：2024-01-02 12:19:05
• 【用途一】
  用于生产高效低残留杀虫杀螨剂毒死蜱、甲基毒死蜱等
  【用途二】
  2-羟基-3，5，6-三氯吡啶又名三氯吡啶醇，是有机磷杀虫剂毒死蜱、甲基毒死蜱的中间体，工业上用其钠盐。

名称

• 中文名: 3,5,6-三氯吡啶-2-醇钠
• 英文名: 3,5,6-Trichloropyridin-2-ol Sodium
• 中文别名: 三氯吡啶醇钠
• 英文别名: sodium 3,5,6-trichloropyridin-2-olate; EINECS 253-506-0; 2-pyridinol, 3,5,6-trichloro-, sodium salt; 2-pyridinol, 3,5,6-trichloro-, sodium salt (1:1); Sodium 3,5,6-trichloro-2-oxo-2H-pyridin-1-ide; 3,5,6-Trichloro-2-oxo-2H-pyridin-1-ide de sodium; Natrium-3,5,6-trichlor-2-oxo-2H-pyridin-1-id; Sodium 3,5,6-trichloro-2-pyridinolate; 3,5,6-Trichloro-2-pyridinol sodium salt; MFCD08704561

物化性质

• 沸点: 325ºC at 760 mmHg
• 分子式: C₅HCl₃NNaO
• 分子量: 220.416
• 闪点: 150.4ºC
• 精确质量: 218.902145
• PSA: 35.95000
• LogP: 3.18560
• 外观性状: 灰白色粉末
• 储存条件: 室温，密封

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: Sodium 3,5,6-trichloropyridin-2-olate Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:Sodium 3,5,6-trichloropyridin-2-olate CAS number:37439-34-2 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C5HCl3NO.Na Molecular weight:220.4 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933399090

制备

【方法一】
三氯吡啶醇的工业合成有两条路线。
(1)将吡啶氯化制成2，3，5，6-四氯吡啶，然后将该四氯吡啶用氢氧化钠碱解制成三氯吡啶醇钠盐。
(2)用三氯乙酰氯与丙烯腈反应，得到三氯吡啶醇，再碱解得到其钠盐。
在1500L搪瓷反应釜中投入280kg三氯乙酰氯，过量丙烯腈及适量的溶剂和催化剂，升温回流反应，用气相色谱控制终点。当酰氯转化完毕后(约14h)即可停止反应，然后将反应物抽入蒸馏釜，减压脱溶。脱出的溶剂回收套用，溶剂脱尽后，将残余物抽入碱解釜，慢慢滴加30％NaOH进行碱解，控制温度在20～40℃。过滤，得到三氯吡啶醇钠盐湿品，即可直接进入下一步反应。
从反应历程出发，也可控制反应分三步完成。由此可有效控制副产物生成，提高反应收率和产品质量。
目前这两种工艺都可以生产，而用吡啶为原料时，反应过程中腐蚀性强，但产品质量好。
三氯吡啶醇钠湿品为灰黄色固体物。

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%