76360-82-2

• 常用中文名：2-(甲硫基)-4-(甲氨基)嘧啶-5-甲酸乙酯
• 常用英文名：4-(Methylamino)-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester
• CAS号：76360-82-2
• 分子式：C₉H₁₃N₃O₂S
• 分子量：227.28300
• 相关类别： 医药中间体 杂环化合物 嘧啶类化合物 硫基嘧啶
• 发布时间：2018-06-20 19:18:12
• 更新时间：2024-01-04 18:16:41

名称

• 中文名: 4-甲胺基-2-甲硫基-5-嘧啶甲酸乙酯
• 英文名: ethyl 4-(methylamino)-2-methylsulfanylpyrimidine-5-carboxylate
• 中文别名: 2-(甲硫基)-4-(甲氨基)嘧啶-5-甲酸乙酯; 4-(甲基氨基)-2-(甲基磺酰基)-5-嘧啶羧酸乙酯
• 英文别名: ethyl 4-(methylamino)-2-(methylthio)pyrimidine-5-carboxylate; 4-Methylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester; ethyl 4-methylamino-2-methylsulfanylpyrimidine-5-carboxylate; 4-(Methylamino)-2-(methylthio)pyrimidine-5-carboxylic Acid Ethyl Ester; 4-methylamino-2-methanesulfanyl-pyrimidine-5-carboxylic acid ethyl ester; Ethyl4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate

物化性质

• 密度: 1.24 g/cm3
• 沸点: 368.9ºC at 760 mmHg
• 分子式: C₉H₁₃N₃O₂S
• 分子量: 227.28300
• 闪点: 176.9ºC
• 精确质量: 227.07300
• PSA: 89.41000
• LogP: 1.48990
• 储存条件: 室温，干燥

安全

• 海关编码: 2933599090

合成路线

5909-24-0 74-89-5 ~94% 76360-82-2

文献：Goldstein, David M.; Soth, Michael; Gabriel, Tobias; Dewdney, Nolan; Kuglstatter, Andreas; Arzeno, Humberto; Chen, Jeffrey; Bingenheimer, William; Dalrymple, Stacie A.; Dunn, James; Farrell, Robert; Frauchiger, Sandra; La Fargue, Joann; Ghate, Manjiri; Graves, Bradford; Hill, Ronald J.; Li, Fujun; Litman, Renee; Loe, Brad; McIntosh, Joel; McWeeney, Daniel; Papp, Eva; Park, Jaehyeon; Reese, Harlan F.; Roberts, Richard T.; Rotstein, David; San Pablo, Bong; Sarma, Keshab; Stahl, Martin; Sung, Man-Ling; Suttman, Rebecca T.; Sjogren, Eric B.; Tan, Yunchou; Trejo, Alejandra; Welch, Mary; Weller, Paul; Wong, Brian R.; Zecic, Hasim Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2255 - 2265

5909-24-0 ~% 76360-82-2

文献：US2003/171584 A1, ;

5909-24-0 593-51-1 ~% 76360-82-2

文献：WO2011/75616 A1, ; Page/Page column 62 ;

5909-24-0 ~81% 76360-82-2 185040-32-8

文献：Warner-Lambert Company Patent: US5733914 A1, 1998 ;

上下游产品

上游产品  3
5909-24-0 74-89-5 593-51-1
下游产品  9
185039-37-6 185039-48-9 185039-46-7 17759-30-7
185040-32-8 185039-29-6 863028-98-2 449811-92-1
449811-01-2

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%