185039-29-6

• 常用中文名：6-(2,6-二氯苯基)-8-甲基-2-甲基磺酰基-8H-吡啶并[2,3-d]-嘧啶-7-胺
• 常用英文名：6-(2,6-Dichlorophenyl)-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-imine
• CAS号：185039-29-6
• 分子式：C₁₅H₁₂Cl₂N₄S
• 分子量：351.25400
• 发布时间：2018-06-26 11:46:59
• 更新时间：2026-08-14 18:39:53

名称

• 中文名: 6-(2,6-二氯苯基)-8-甲基-2-甲基磺酰基-8H-吡啶并[2,3-d]-嘧啶-7-胺
• 英文名: 6-(2,6-dichlorophenyl)-8-methyl-2-methylsulfanylpyrido[2,3-d]pyrimidin-7-imine
• 中文别名: 6-(2,6-二氯苯基)-8-甲基-2-(甲硫基)吡啶并[2,3-D]嘧啶-7(8H)-亚胺
• 英文别名: 6-(2,6-Dichlorophenyl)-8-Methyl-2-Methylsulfanyl-8H-pyrido[2,3-d]-pyriMidin-7-ylideneaMine; Pyrido[2,3-d]pyrimidin-7(8H)-imine, 6-(2,6-dichlorophenyl)-8-methyl-2-(methylthio)

物化性质

• 密度: 1.48g/cm3
• 沸点: 501.8ºC at 760 mmHg
• 分子式: C₁₅H₁₂Cl₂N₄S
• 分子量: 351.25400
• 闪点: 257.3ºC
• 精确质量: 350.01600
• PSA: 79.86000
• LogP: 4.24320
• 蒸汽压: 3.36E-10mmHg at 25°C
• 折射率: 1.71

合成路线

3215-64-3 185040-32-8 ~45% 185039-29-6

文献：Klutchko, Sylvester R.; Hamby, James M.; Boschelli, Diane H.; Wu, Zhipei; Kraker, Alan J.; Amar, Aneesa M.; Hartl, Brian G.; Shen, Cynthia; Klohs, Wayne D.; Steinkampf, Randall W.; Driscoll, Denise L.; Nelson, James M.; Elliott, William L.; Roberts, Billy J.; Stoner, Chad L.; Vincent, Patrick W.; Dykes, Donald J.; Panek, Robert L.; Lu, Gina H.; Major, Terry C.; Dahring, Tawny K.; Hallak, Hussein; Bradford, Laura A.; Showalter, H. D. Hollis; Doherty, Annette M. Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3276 - 3292

3215-64-3 ~38% 185039-29-6

文献：Warner-Lambert Company Patent: US5945422 A1, 1999 ; US 5945422 A

17759-30-7 ~% 185039-29-6

文献：Journal of Medicinal Chemistry, , vol. 41, # 17 p. 3276 - 3292

5909-24-0 ~% 185039-29-6

文献：Journal of Medicinal Chemistry, , vol. 41, # 17 p. 3276 - 3292

76360-82-2 ~% 185039-29-6

文献：Journal of Medicinal Chemistry, , vol. 41, # 17 p. 3276 - 3292