404844-02-6

• 常用中文名：N-去甲基伊马替尼
• 常用英文名：N-Desmethyl imatinib
• CAS号：404844-02-6
• 分子式：C₂₈H₂₉N₇O
• 分子量：479.57600
• 相关类别： 原料药 抗肿瘤药 替尼类抗肿瘤药
• 发布时间：2018-09-14 18:35:00
• 更新时间：2026-07-11 19:01:10
• N-Desmethyl Imatinib是Imatinib的代谢物。

名称

• 中文名: N-去甲基伊马替尼
• 英文名: N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-(piperazin-1-ylmethyl)benzamide
• 中文别名: 伊马替尼去甲基(甲酸); 伊马替尼N-脱甲基杂质; 伊马替尼杂质C(N-去甲基伊马替尼); 伊马替尼杂质6(伊马替尼杂质C); 去甲基伊马替尼D8; 伊马替尼去甲杂质; N-去甲伊马替尼D8; N-去甲基伊马替尼,10 MM DMSO 溶液; N-Desmethyl imatinib试剂; 伊马尼替杂质F; N-去甲伊马替尼; 伊马替尼进口标准杂质A; 氮位N-脱甲基伊马替尼; 伊马替尼杂质C; N 去甲基伊马替尼-氘4; 去甲基伊马替尼; 甲磺酸伊马替尼杂质1; 甲磺酸伊马替尼杂质H; 伊马替尼代谢物; N-去甲基伊马替尼-[D4]; 去甲基伊马替尼(杂质); N-去甲基伊马替尼 (杂质); 伊马替尼杂质C(N-二甲基伊马替尼); N-(4-甲基-3-((4-(吡啶-3-基)嘧啶-2-基)氨基)苯基)-4-(哌嗪-1-基甲基)苯甲酰胺
• 英文别名: Desmethyl imatinib D4Q: What is Desmethyl imatinib D4 Q: What is the CAS Number of Desmethyl imatinib D4 Q: What is the storage condition of Desmethyl imatinib D4 Q: What e the applications of Desmethyl imatinib D4; Imatinib Impurity C (Imatinib (Piperazine)-N1- Oxide) (crude); N-Desmethyl lmatinib; Imatinib Mesylate Imp C (phmeuropa): N-4-methyl-3-4-(3-pyridinyl)-2-pyrimidinylaminophenyl-4-(1-piperazinyl methyl)benzamide; Imatinib Imp.F; Imatinib N-Desmethyl ImpurityQ: What is Imatinib N-Desmethyl Impurity Q: What is the CAS Number of Imatinib N-Desmethyl Impurity Q: What is the storage condition of Imatinib N-Desmethyl Impurity Q: What e the applications of Imatinib N-Desmethyl Impurity; Imatinib Impurity 6(Imatinib Impurity C); IMATINIB METABOLITE N-DESMETHYL IMATINIB (N-DESMETHYL IMATINIB); N-methylimatinib; N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-benzamide; DesMethyl IMatinib-d8; N-Desmethyl imatinib, 10 mM in DMSO; IMatinib N-DesMethyl IMpurity; N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}-4; Imatinib Impurity C; Imatinib Impurity F; Imatinib metabolite; Imatinib Impurity 6(EP-C); no mesylate; Inhibitor,N Desmethyl imatinib,v-Abl,PDGFR,inhibit,NDesmethyl imatinib,Drug Metabolite,Imatinib,N-Desmethyl imatinib,c-Kit; N-Demethylimatinib(Impurity); N-Desmethyl Imatinib Impurity; Imatinib Impurity C (Imatinib (Piperidine)-N4- Oxide); DesMethyl IMatinib; N-{4-Methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}-4-(piperazin-1-ylmethyl)benzamide; iMatinib related substance A; Benzamide,N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl); Imatinib impurity 6/Imatinib Impurity C/N-Desmethyl Imatinib/N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(piperazin-1-ylmethyl)benzamide; CGP-74588; Imatinib Impurity C (Imatinib N-Desmethyl Impurity); N-Desmethyl Gleevec; Imatinib Impurity 6（-C）; Norimatinib; Imatinib Impurity C (N-Desmethyl Imatinib); 4-[(1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino] phenyl]benzamide; N-Desmethyl Imatinib; Imatinib metabolite N-Desmethyl Imatinib; N-DesmethyL

物化性质

• 密度: 1.269g/cm3
• 熔点: 99-101ºC
• 分子式: C₂₈H₂₉N₇O
• 分子量: 479.57600
• 精确质量: 479.24300
• PSA: 95.07000
• LogP: 4.66080
• 外观性状: 灰白色至灰白的-黄色固体
• 折射率: 1.676
• 储存条件: -20°C Freezer

生物活性

• 描述: N-Desmethyl Imatinib是Imatinib的代谢物。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他

安全

• 安全声明 (欧洲): 24/25
• 海关编码: 29339900