65567-32-0

• 常用中文名：(R)-(-)-苯乙基内酰脲
• 常用英文名：(R)-(-)-N-[1-(1-NAPHTHYL)ETHYL]-3,5-DINITROBENZAMIDE
• CAS号：65567-32-0
• 分子式：C₁₁H₁₂N₂O₂
• 分子量：204.22500
• 发布时间：2018-04-02 08:00:00
• 更新时间：2026-07-02 11:26:27
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名称

• 中文名: (R)-(-)-苯乙基内酰脲
• 英文名: (5R)-5-ethyl-5-phenylimidazolidine-2,4-dione
• 中文别名: 美芬妥英杂质5; 5-乙基-5-苯基海因; (R)-5-乙基-5-苯基咪唑烷-2,4-二酮
• 英文别名: 5-ethyl-5-phenyl-4-imidazolidinedion(r); (R)-(-)-5-ETHYL-5-PHENYLHYDANTOIN; (R)-(-)-NIRVANOL; l-5-ethyl-5-phenylhydantoin; l-nirvanol; (R)-(-)-5-Ethyl-5-phenyl-2,4-imidazolidinedione, (R)-(-)-5-Ethyl-5-phenylhydantoin; R-(-)-N-DESMETHYLMHENTOIN; 2,4-Imidazolidinedione, 5-ethyl-5-phenyl-, (R)- (9CI); (5r)-5-ethyl-5-phenyliMidazolidine-2,4-dione; (R)-()-Nirvanol//65-0; (R)-5-Ethyl-5-phenylimidazolidine-2,4-dione; (R)-(-)-5-ETHYL-5-PHENYL-2,4-IMIDAZOLIDINEDIONE; 2,4-Imidazolidinedione, 5-ethyl-5-phenyl-, (5R); Brn; Mhenytoin Impurity 5

物化性质

• 分子式: C₁₁H₁₂N₂O₂
• 分子量: 204.22500
• 精确质量: 204.09000
• PSA: 58.20000
• LogP: 1.78890

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MU2452100 CHEMICAL NAME : Hydantoin, 5-ethyl-5-phenyl-, (-)- CAS REGISTRY NUMBER : 65567-32-0 BEILSTEIN REFERENCE NO. : 0085312 LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C11-H12-N2-O2 MOLECULAR WEIGHT : 204.25 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - child DOSE/DURATION : 105 mg/kg TOXIC EFFECTS : Skin and Appendages - dermatitis, allergic (after systemic exposure) Nutritional and Gross Metabolic - body temperature increase REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 47,209,1933 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BBIADT Biomedica Biochimica Acta. (Akademie-Verlag GmbH, Postfach 1233, Berlin DDR-1086, Ger. Dem. Rep.) V.42- 1983- Volume(issue)/page/year: 46,623,1987 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 125 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 47,209,1933 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 47,209,1933 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal DOSE : 97 mg/kg SEX/DURATION : female 10 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 221,228,1982

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302-H315-H319-H335
• 警示性声明: P261-P305 + P351 + P338
• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xn
• 风险声明 (欧洲): 22-36/37/38
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 2
• RTECS号: MU2452000
• 海关编码: 2933990090

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海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%