99010-63-6

• 常用中文名：1-异丁基-1H-咪唑并[4,5-c]喹啉 5-氧化物
• 常用英文名：1H-Imidazo[4,5-c]quinoline, 1-(2-methylpropyl)-, 5-oxide
• CAS号：99010-63-6
• 分子式：C₁₄H₁₅N₃O
• 分子量：241.28800
• 发布时间：2018-12-26 11:14:06
• 更新时间：2026-07-04 16:32:46

名称

• 中文名: 1-(2-甲基丙基)-1H-咪唑并[4,5-c]喹啉 5,n-氧化物
• 英文名: 1-(2-methylpropyl)-5-oxidoimidazo[4,5-c]quinolin-5-ium
• 中文别名: 咪喹莫特相关物质B; 地塞米松杂质36; 1-异丁基-1H-咪唑并[4,5-C]喹啉 N-氧化物; 咪喹莫特杂质2(咪喹莫特相关化合物 B ); 咪喹莫特相关化合物B; 去氨基咪喹莫特 N-氧化物; 1-异丁基-1H-咪唑并[4,5-C]喹啉 5-氧化物; 咪喹莫特相关物质B 标准品; 咪喹莫特杂质1; 咪喹莫特杂质B; 咪喹莫特相关物质B1-(2-甲基丙基)-1H-咪唑并[4,5-C]喹啉 5,N-氧化物
• 英文别名: Imiquimod Related Compound B (25 mg) (1-Isobutyl-1H-imidazo[4,5-c]quinoline 5-oxide); 1-（2- Methylpropyl）1H-imidazo[4,5-c] Quinoline N-oxide; Imiquimod RC B; DesaMino IMiquiMod N-Oxide; Imiquimod related Substance B; Imiquimod Related Compound B; 1-Isobutyl-1H-imidazo[4,5-c]quinoline 5-Oxide (Desaminoimiquimod N-Oxide); 1-Isobutyl-1H-imidazo[4,5-c]quinoline 5-oxide; Dexamethasone Impurity 36; 1-Isobutyl-1H-imidazo[4,5-c]quinoline N-oxide; Imiquimod Impurity 2 (Imiquimod Related Compound B); Imiquimod Related Compound B (1-Isobutyl-1H-imidazo[4,5-c]quinoline 5-oxide); imi051; 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline 5N-oxide

物化性质

• 分子式: C₁₄H₁₅N₃O
• 分子量: 241.28800
• 精确质量: 241.12200
• PSA: 43.28000
• LogP: 3.27400
• 储存条件: 室温，干燥，密封

安全

• 危害码 (欧洲): Xi
• 危险品运输编码: NONH for all modes of transport

合成路线

99010-24-9 ~% 99010-63-6

文献：Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

99010-09-0 122-51-0 ~% 99010-63-6

文献：Riker Laboratories, Inc. Patent: US4689338 A1, 1987 ; US 4689338 A

99009-85-5 ~% 99010-63-6

文献：Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

611-36-9 ~% 99010-63-6

文献：Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

50332-66-6 ~% 99010-63-6

文献：Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

39061-97-7 ~% 99010-63-6

文献：Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

99010-09-0 ~% 99010-63-6

文献：Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491