1001129-81-2

• 常用中文名：LKY-047
• 常用英文名：LKY-047
• CAS号：1001129-81-2
• 分子式：C₂₃H₁₉NO₇
• 分子量：421.39900
• 发布时间：2018-02-11 01:29:14
• 更新时间：2023-01-15 12:23:23
• LKY-047 is a decursin derivative that potently and selectively inhibits CYP2J2, competitively inhibits CYP2J2-mediated astemizole O-demethylase and terfenadine hydroxylase activity with Ki of 0.96 and 2.61 uM, respectively.

名称

• 英文名: (7S)-(+)-3-(4-nitrophenyl)acrylic acid, 8,8-dimethyl-2-oxo-6,7-dihydro-2H,8H-pyrano[3,2-g]chromen-7-yl ester
• 英文别名: 3-(4-nitro-phenyl)-acrylic acid 2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H-pyrano[3,2-g]chromen-3-yl ester

物化性质

• 分子式: C₂₃H₁₉NO₇
• 分子量: 421.39900
• 精确质量: 421.11600
• PSA: 111.56000
• LogP: 4.56310