357952-10-4

• 常用中文名：Urocortin III,小鼠
• 常用英文名：Urocortin III (mouse) trifluoroacetate salt
• CAS号：357952-10-4
• 分子式：C₁₈₆H₃₁₂N₅₂O₅₂S₂
• 分子量：4172.97
• 相关类别： 信号通路 G 蛋白偶联受体/G 蛋白 CRFR
• 发布时间：2018-03-16 14:12:40
• 更新时间：2026-07-07 19:40:34
• Urocortin III, mouse 是促肾上腺皮质激素释放因子 (CRF) 的相关肽。Urocortin III 优先结合并激活 CRF-R2。

名称

• 中文名: Urocortin III,小鼠
• 英文名: Urocortin III, mouse
• 中文别名: 促肾上腺皮质激素释放因子 (CRF) 相关肽UROCORTIN III, MOUSE; 尿皮质素III UROCORTIN III, MOUSE, AMIDE; 小鼠尿皮质素II; 小鼠 UROCORTIN III肽; 尿皮质素III UROCORTIN III, MOUSE; 小鼠尿皮质素III
• 英文别名: Stresscopin (Mouse), S (Mouse), Ucn III (Mouse); PHE-THR-LEU-SER-LEU-ASP-VAL-PRO-THR-ASN-ILE-MET-ASN-ILE-LEU-PHE-ASN-ILE-ASP-LYS-ALA-LYS-ASN-LEU-G-ALA-LYS-ALA-ALA-ALA-ASN-ALA-GLN-LEU-MET-ALA-GLN-ILE-NH2; STRESSCOPIN (MOUSE) TRIFLUOROACETATE SALT; Urocortin III, mouse, Amide; S (MOUSE) TRIFLUOROACETATE SALT; S (MOUSE); UCN-II MOUSE; UROCORTIN III (MOUSE); UCN-II; (2R)-2-[(1S,2S,4aS,4bR,6aR,10aR,10bS,12aS)-2,4b,6a,9,9,10b,12a-Heptamethyl-1-(2-oxoethyl)octadecahydro-2-chrysenyl]propanoic acid; H-Val-Ile-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-g-Ile-Leu-Leu-Glu-Gln-Ala-g-Tyr-Lys-Ala-Ala-g-Asn-Gln-Ala-Ala-Thr-Asn-Ala-Gln-Ile-Leu-Ala-His-Val-NH2; FTLSLDVPTNIMNILFNIDKAKNAKAAANAQLMAQI-NH2; Stresscopin (mouse); UROCORTIN III (MOUSE) TRIFLUOROACETATE SALT; UCN III (MOUSE) TRIFLUOROACETATE SALT; VAL-ILE-LEU-SER-LEU-ASP-VAL-PRO-ILE-GLY-LEU-LEU-G-ILE-LEU-LEU-GLU-GLN-ALA-G-TYR-LYS-ALA-ALA-G-ASN-GLN-ALA-ALA-THR-ASN-ALA-GLN-ILE-LEU-ALA-HIS-VAL-NH2; Urocortin III, mouse FTLSLDVPTNIMNILFNIDKAKNAKAAANAQLMAQI-NH2; H-PHE-THR-LEU-SER-LEU-ASP-VAL-PRO-THR-ASN-ILE-MET-ASN-ILE-LEU-PHE-ASN-ILE-ASP-LYS-ALA-LYS-ASN-LEU-G-ALA-LYS-ALA-ALA-ALA-ASN-ALA-GLN-LEU-MET-ALA-GLN-ILE-NH2

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 536.7±23.0 °C at 760 mmHg
• 分子式: C₁₈₆H₃₁₂N₅₂O₅₂S₂
• 分子量: 4172.97
• 闪点: 292.4±19.1 °C
• 精确质量: 458.376007
• LogP: 10.00
• 蒸汽压: 0.0±3.1 mmHg at 25°C
• 折射率: 1.497

生物活性

• 描述: Urocortin III, mouse 是促肾上腺皮质激素释放因子 (CRF) 的相关肽。Urocortin III 优先结合并激活 CRF-R2。
• 相关类别:
  研究领域 >> 心血管疾病
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> CRFR
• 参考文献:

  [1]. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7570-5. Lewis K, et al. Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor. Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor.