39929-79-8

• 常用中文名：2,4-二羟基吡咯[2,3-d]嘧啶
• 常用英文名：7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol
• CAS号：39929-79-8
• 分子式：C₆H₅N₃O₂
• 分子量：151.123
• 相关类别： 医药中间体 杂环化合物 嘧啶类化合物 羟基嘧啶
• 发布时间：2018-12-25 01:04:31
• 更新时间：2026-07-17 14:24:44

名称

• 中文名: 2,4-二羟基吡咯[2,3-d]嘧啶
• 英文名: 2,4-Dihydroxypyrrolo[2,3-d]Pyrimidine
• 中文别名: 2,4-二羟基吡咯并[2,3-d]嘧啶; 2,4-二羟基-7H-吡咯并[2,3-D嘧啶; 1H-吡咯[2,3-D]嘧啶-2,4(3H,7H)-二酮; 2,4-二羟基吡咯并[2,3-D]嘧啶; 4-羟基-6,36-二甲氧基喹啉; 托法替布杂质03; 7H-吡咯并[2,3-D]嘧啶-2,4-二醇
• 英文别名: 2,4-Dihydroxypyrrolo[2,3-d]pyrimidine; Tofacitinib Impurity; 1,7-DIHYDRO-PYRROLO[2,3-D]PYRIMIDINE-2,4-DIONE; 39-8; T56 BM GN INJ FQ HQ; 2,4-Dihydroxy-7-deazapurine; T56 BM FVMVMJ; 4-hydroxy-1,5-dihydropyrrolo[3,2-d]pyrimidin-6-one; 7H-Pyrrlo[2,3-d]pyrimidine-2,4-diol; 1H-Pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione; 2,4-hydroxy-7H-pyrrolo-[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol ISO 9001：2015 REACH; 2,4-Dihydroxy-7H-pyrrolo-(2,3-d)pyrimidine; 1,7-dihydropyrrolo[2,3-d]pyrimidine-2,4-dione; 2,6-Dihydroxy-7-deazapurine; 4,6-DIHYDROXY PYRROLO PYRIMIDINE; 7-Deazaxanthine; 1,7-dihydro-2H-pyrrolo[2,3-d]pyrimidine-2,4(3H)-dione; 1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidine-2,4-dione; 2,4-Dihydroxy-1H-pyrrolo[2,3-d]pyrimidine; 1H-PYRROLO-[2,3-D]-PYRIMIDINE-2,4(3H,7H)-DIONE; 7H-Pyrrolo2,3-dpyrimidin-2,4-diol; 7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol; 2,4-Dihydroxy-7H-pyrrolo[2,3-d]pyrimidine, 2,6-Dihydroxy-7-deazapurine

物化性质

• 密度: 1.8±0.1 g/cm3
• 沸点: 607.6±58.0 °C at 760 mmHg
• 熔点: >250ºC
• 分子式: C₆H₅N₃O₂
• 分子量: 151.123
• 闪点: 321.2±32.3 °C
• 精确质量: 151.038177
• PSA: 82.03000
• LogP: -1.03
• 外观性状: 粉红色至棕色固体
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.863
• 储存条件: -20°C Freezer

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

107-20-0 873-83-6 ~98% 39929-79-8

文献：Chen, Zecheng; Venkatesan, Aranapakam M.; Dehnhardt, Christoph M.; Ayral-Kaloustian, Semiramis; Brooijmans, Natasja; Mallon, Robert; Feldberg, Larry; Hollander, Irwin; Lucas, Judy; Yu, Ker; Kong, Fangming; Mansour, Tarek S. Journal of Medicinal Chemistry, 2010 , vol. 53, # 8 p. 3169 - 3182

52133-67-2 57-13-6 ~90% 39929-79-8

文献：Xie, Hui; Zeng, Lili; Zeng, Shaogao; Lu, Xin; Zhang, Guicheng; Zhao, Xin; Cheng, Na; Tu, Zhengchao; Li, Zhiyuan; Xu, Hongjiang; Yang, Ling; Zhang, Xiquan; Huang, Min; Zhao, Junling; Hu, Wenhui European Journal of Medicinal Chemistry, 2012 , vol. 52, p. 205 - 212

102879-75-4 ~81% 39929-79-8

文献：VERNALIS (R and D) LTD. Patent: WO2007/104944 A1, 2007 ; Location in patent: Page/Page column 38 ;

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%