143984-17-2

• 常用中文名：Y 29794
• 常用英文名：Y 29794
• CAS号：143984-17-2
• 分子式：C₃₀H₄₂N₂O₄S₃
• 分子量：590.86
• 发布时间：2018-07-09 08:24:03
• 更新时间：2024-02-04 15:06:14
• Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopeptidase (PPCE) inhibitor. Y-29794 selectively and competitively inhibited rat brain PPCE (Ki = 0.95 nM) in a reversible manner. Ex vivo study demonstrated that Y-29794 could penetrate into brain to exhibit dose-dependent and long-lasting inhibition. Furthermore, Y-29794 could potentiate the effect of TRH on the release of ACh in the rat hippocampus. Y-29794 prevents the progression of A beta-like deposition in the hippocampus of the SAM.

名称

• 英文名: Y-29794 tosylate

物化性质

• 分子式: C₃₀H₄₂N₂O₄S₃
• 分子量: 590.86