143984-17-2
143984-17-2 structure
- Name: Y 29794
- Chemical Name: Y-29794 tosylate
- CAS Number: 143984-17-2
- Molecular Formula: C30H42N2O4S3
- Molecular Weight: 590.86
- Create Date: 2018-07-09 08:24:03
- Modify Date: 2025-09-02 09:17:55
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Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopeptidase (PPCE) inhibitor. Y-29794 selectively and competitively inhibited rat brain PPCE (Ki = 0.95 nM) in a reversible manner. Ex vivo study demonstrated that Y-29794 could penetrate into brain to exhibit dose-dependent and long-lasting inhibition. Furthermore, Y-29794 could potentiate the effect of TRH on the release of ACh in the rat hippocampus. Y-29794 prevents the progression of A beta-like deposition in the hippocampus of the SAM.
| Name | Y-29794 tosylate |
|---|
| Molecular Formula | C30H42N2O4S3 |
|---|---|
| Molecular Weight | 590.86 |