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| 中文名 | 莫瑞伐定 |
|---|---|
| 英文名 | murepavadin |
| 英文别名 |
1H,5H-Dipyrrolo[1,2-a:1',2'-d][1,4,7,10,13,16,19,22,25,28,31,34,37,40]tetradecaazacyclodotetracontine-5,10,13,16,19,22,25,28,31,34,37,40,43,46(46aH)-tetradecone, 17,20,26,29,35-pentakis(2-aminoethyl)-32-(3-aminopropyl)triacontahydro-44-[(1R)-1-hydroxyethyl]-11-(hydroxymethyl)-23,41-bis(1H-indol-3-ylmethyl)-14-methyl-38-[(1S)-1-methylpropyl]-, (5aR,11S,14S,17S,20S,23S,26S,29R,32S,35S,38S,41S,44S,46aS)-
10070 (5aR,11S,14S,17S,20S,23S,26S,29R,32S,35S,38S,41S,44S,46aS)-17,20,26,29,35-Pentakis(2-aminoethyl)-32-(3-aminopropyl)-38-[(2S)-2-butanyl]-44-[(1R)-1-hydroxyethyl]-11-(hydroxymethyl)-23,41-bis(1H-indol-3-ylmethyl)-14-methyltriacontahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d][1,4,7,10,13,16,19,22,25,28,31,34,37,40]tetradecaazacyclodotetracontine-5,10,13,16,19,22,25,28,31,34,37,40,43,46(46aH)-tetradecone murepavadin |
| 描述 | Murepavadin(POL7080)是一种高效,特异的大环假单胞菌抗生素,用于治疗由铜绿假单胞菌引起的细菌感染。细菌感染3期临床 |
|---|---|
| 参考文献 | References 1. Bassetti M, et al. Curr Opin Infect Dis. 2018 Jan 13. doi: 10.1097/QCO.0000000000000438. View Related Products by Target Bacterial Bacterial Infection |
| 密度 | 1.4±0.1 g/cm3 |
|---|---|
| 沸点 | 1894.3±65.0 °C at 760 mmHg |
| 分子式 | C73H112N22O16 |
| 分子量 | 1553.808 |
| 闪点 | 1099.4±34.3 °C |
| 精确质量 | 1552.862671 |
| LogP | -9.89 |
| 蒸汽压 | 0.0±0.3 mmHg at 25°C |
| 折射率 | 1.660 |
| 储存条件 | -20°C，避光保存于惰性气体中 |