英文名 | 5-Methyl-N-(3-pyridinyl)-3,5-dihydropyrrolo[2,3-f]indole-1(2H)-carboxamide hydrochloride (1:1) |
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英文别名 |
5-Methyl-N-(pyridin-3-yl)-3,5-dihydropyrrolo[2,3-f]indole-1(2H)-carboxamide hydrochloride (1:1)
Pyrrolo[2,3-f]indole-1(2H)-carboxamide, 3,5-dihydro-5-methyl-N-3-pyridinyl-, hydrochloride (1:1) 5-Methyl-N-(3-pyridinyl)-3,5-dihydropyrrolo[2,3-f]indole-1(2H)-carboxamide hydrochloride (1:1) MFCD01530064 |
描述 | SB 206553是一种有效的选择性5-HT2B/5-HT2C受体拮抗剂,大鼠5-HT2B的pA2为8.89,人5-HT2C的pKi为7.92,对其他5-HT受体亚型的选择性显示>80倍;表现出抗焦虑样体外和体内特性。焦虑停止了 |
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参考文献 | References 1. Forbes IT, et al. J Med Chem. 1995 Jul 7;38(14):2524-30. 2. Upton N, et al. Eur J Pharmacol. 1998 Oct 16;359(1):33-40. 3. Kennett GA, et al. Br J Pharmacol. 1996 Feb;117(3):427-434. 4. Porras G, et al. Neuropsychopharmacology. 2002 Mar;26(3):311-24. View Related Products by Target 5-HT Receptor Anxiety |
分子式 | C17H17ClN4O |
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分子量 | 328.796 |
精确质量 | 328.109100 |