| 英文名 | N-{4-[(1R)-1-Hydroxy-2-(isopropylamino)ethyl]phenyl}methanesulfonamide |
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| 英文别名 |
N-{4-[(1R)-1-Hydroxy-2-(isopropylamino)ethyl]phenyl}methanesulfonamide
Methanesulfonamide, N-[4-[(1R)-1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]- N-{4-[(1R)-1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide |
| 描述 | (-)-索他洛尔是一种非选择性竞争性β-肾上腺素能受体阻滞剂,也具有III类抗心律失常特性。 |
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| 参考文献 | 1. Darpo B, Karnad DR, Badilini F, Florian J, Garnett CE, Kothari S, Panicker GK, Sarapa N. Are women more susceptible than men to drug-induced QT prolongation? Concentration-QTc modelling in a phase 1 study with oral rac-sotalol. Br J Clin Pharmacol. 2014 Mar;77(3):522-31. doi: 10.1111/bcp.12201. PubMed PMID: 23819796; PubMed Central PMCID: PMC4371537. |
| 密度 | 1.2±0.1 g/cm3 |
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| 沸点 | 443.3±55.0 °C at 760 mmHg |
| 分子式 | C12H20N2O3S |
| 分子量 | 272.364 |
| 闪点 | 221.9±31.5 °C |
| 精确质量 | 272.119476 |
| LogP | 0.32 |
| 蒸汽压 | 0.0±1.1 mmHg at 25°C |
| 折射率 | 1.571 |