113028-17-4

• 常用中文名：6-氟-7-哌嗪-1-甲基-4-氧代-[1,3]硫氮杂环[3,2-a]喹啉-3-羧酸乙酯
• 常用英文名：Ethyl 6-fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate
• CAS号：113028-17-4
• 分子式：C₁₈H₂₀FN₃O₃S
• 分子量：363.406
• 发布时间：2019-01-09 07:20:55
• 更新时间：2024-01-02 10:36:19

名称

• 中文名: 6-氟-7-哌嗪-1-甲基-4-氧代-[1,3]硫氮杂环[3,2-a]喹啉-3-羧酸乙酯
• 英文名: Ethyl 6-fluoro-1-methyl-4-oxo-7-(1-piprazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate
• 中文别名: 普卢利沙星中间体二; 6-氟-1-甲基-4-氧代-7-(1-哌嗪基)4H-(1,3)噻嗪(3,2A)并喹啉-3-羧酸乙酯 (PL-10); 普卢利沙星中间体PL-10
• 英文别名: Ethyl 6-fluoro-4-oxo-7-piperazin-1-yl-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate; ulifloxacin ethyl ester; Prulifloxacin Intermediate PL-10; Ethyl 6-fluoro-4-oxo-7-(1-piperazinyl)-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate; T B466 BN DS GV CHJ FVO2 JF K- DT6M DNTJ; 1H,4H-[1,3]Thiazeto[3,2-a]quinoline-3-carboxylic acid, 6-fluoro-4-oxo-7-(1-piperazinyl)-, ethyl ester; Ethyl 6-fluoro-4-oxo-7-(1-piperazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate; PRULIFLOXACIN INTERMEDIATE 2; MFCD08063938

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 581.1±50.0 °C at 760 mmHg
• 分子式: C₁₈H₂₀FN₃O₃S
• 分子量: 363.406
• 闪点: 305.2±30.1 °C
• 精确质量: 363.105286
• PSA: 88.87000
• LogP: 1.87
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.679
• 储存条件: 2-8°C，避光，保存于惰性气体中

安全

• 海关编码: 2933990090

合成路线

110-85-0 113046-72-3 ~85% 113028-17-4

文献：Segawa, Jun; Kitano, Masahiko; Kazuno, Kenji; Matsuoka, Masato; Shirahase, Ichiro; et al. Journal of Medicinal Chemistry, 1992 , vol. 35, # 25 p. 4727 - 4738

113028-75-4 ~% 113028-17-4

文献：Journal of Medicinal Chemistry, , vol. 35, # 25 p. 4727 - 4738

144514-15-8 ~% 113028-17-4

文献：Journal of Medicinal Chemistry, , vol. 35, # 25 p. 4727 - 4738

3863-11-4 ~% 113028-17-4

文献：Journal of Medicinal Chemistry, , vol. 35, # 25 p. 4727 - 4738

84339-06-0 ~% 113028-17-4

文献：Journal of Medicinal Chemistry, , vol. 35, # 25 p. 4727 - 4738

113028-77-6 ~% 113028-17-4

文献：Journal of Medicinal Chemistry, , vol. 35, # 25 p. 4727 - 4738

144514-35-2 ~% 113028-17-4

文献：Journal of Medicinal Chemistry, , vol. 35, # 25 p. 4727 - 4738

113028-76-5 ~% 113028-17-4

文献：Journal of Medicinal Chemistry, , vol. 35, # 25 p. 4727 - 4738

上下游产品

上游产品  8
110-85-0 113046-72-3 113028-75-4 144514-15-8
3863-11-4 84339-06-0 113028-77-6 113028-76-5
下游产品  2
112984-60-8 123447-62-1

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%