112984-60-8

• 常用中文名：6-氟-7-哌嗪-1-甲基-4-氧代-[1,3]硫氮杂环[3,2-a]喹啉-3-羧酸
• 常用英文名：UNII:C38638H76Y
• CAS号：112984-60-8
• 分子式：C₁₆H₁₆FN₃O₃S
• 分子量：349.38
• 相关类别： 信号通路 抗感染 细菌
• 发布时间：2018-12-20 19:52:53
• 更新时间：2026-07-10 20:29:56
• Ulifloxacin 是一种广谱的喹诺酮抗生素 (antibiotic)。Ulifloxacin 是 Prulifloxacin (HY-B0024) 的活性代谢物。Ulifloxacin 具有抗菌活性。

名称

• 中文名: 6-氟-7-哌嗪-1-甲基-4-氧-[1,3]硫氮杂环[3,2-a]-喹啉-3-羧酸
• 英文名: 6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid
• 中文别名: 6-氟-7-哌嗪-1-甲基-4-氧代-[1,3]硫氮杂环丁并[3,2-A]喹啉-3-羧酸; 普利沙星中间体9; 6-氟-1-甲基-4-氧代-7-(1-哌嗪基)-4H-(1,3)噻嗪(3,2A)并喹啉-3-羧酸 (PL-11); 普卢利沙星中间体—11(PL-11); 普卢利沙星中间体 III; 尤利沙星; 普卢利沙星PL-11; 6-氟-1-甲基-4-氧代-7-(1-哌嗪基)-4H-(1,3)噻嗪(3,2a)并喹啉-3-羧酸(PL-11); 普卢利沙星中间体三; 6-氟-1-甲基-4-氧代-7-(1-哌嗪基)-4H-(1,3)硫氮杂环并(3,2-A)喹啉-3-羧酸; 普卢利沙星中间体 III-D8; 乌利沙星; 盐霉素预混剂,普卢利沙星中间体—11(PL-11); Panc 03.27细胞 (人胰腺癌细胞) (STR鉴定正确)CL-0809; 普卢利沙星中间体PL-11; Panc 03.27细胞 (人胰腺癌细胞) (STR鉴定正确); 6-氟-7-哌嗪-1-甲基-4-氧代-4H-[1,3]硫氮杂环丁烷并[3,2-A]喹啉-3-羧酸; 尤利沙星-D8; 6-氟-1-甲基-4-氧代-7-(哌嗪-1-基)-1,4-二氢-[1,3]硫氮杂环丁烷并[3,2-A]喹啉-3-羧酸
• 英文别名: Ulifloxacin; 6-FLUORO-7-PIPERAZINE-1-METHYL-4-OXY-[1,3]THIOAZACYCLIC[3,2-A]-QUINOLINE-3-CBOXYLIC ACID; Prulifloxacin Intermediate PL-11; 6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3)-thiazeto; Panc327; 6-Fluro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3)-thiazeto(3,2-a)quinoline-3-cboxylic Acid; PRULIFLOXACIN INTERMEDIATE 3; 6-Fluoro-1-Methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-cboxylic acid; 6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid; Panc3_27; 6-FLUORO-1-METHYL-4-OXO-7-(1-PIPRAZINYL)-1H,4H-(1,3)THIAZETO(3,2-A)QUINOLINE-3-CBOXYLIC ACID; 6-FLUORO-1-METHYL-4-OXO-7-(1-PIPERAZINYL)-4H-(1,3)THIAZETO(3,2-A)QUINOLINE-3-CBOXYLIC ACID; 6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-cboxy; Panc 3.27; 6-FLUORO-1-METHYL-4-OXO-7-PIPERAZIN-1-YL-4H-2-THIA-8B-AZA-CYCLOBUTA[A] NAPHTHALENE-3-CBOXYLIC ACID; 6-FLUORO-1-METHYL-4-OXO-7-(1-PIPERAZINYL)-4H-(1,3)-HIAZETO(3,2-A)QUINOLINE-3-CBOXYLIC ACID; PL-11; Panc-3_27; 6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-cboxylic; 6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3)-thiazeto(3,2-a)quinoline-3-cboxylic acid cas:(intermediate of prulifloxacin); Prulifloxacin intermediate III; MFCD00882994; 6-Fluoro-1-methyl-4-oxo-7-piperazin; -1-yl-4H-2-thia-8b-aza-cyclobuta[a]; naphthalene-3-carboxylic acid; 6-Fluoro-1-Methyl-4-oxo-7; Panc-327; 1H,4H-[1,3]Thiazeto[3,2-a]quinoline-3-cboxylic acid, 6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl); PL-11 6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H- (1,3)-hiazeto(3,2-a)quinoline-3-cboxylic acid; 6-Fluoro-1-Methyl-4-Oxo-7-(1-Piperazinyl)-4H-(1,3)-Thiazeto(3,2-Alpha)Quinoline-3-Cboxylic Acid; 6-Fluoro-1-methyl-7-(1-piperazinyl)-4-oxo-4H-(1,3)thiazeto(3,2-a)quinoline-3-cboxylic acid; 6-Fluoro-1-Methyl-4-Oxo-7-(1-Piperazinyl)-4H-[1,3]Thiazeto[3,2-A]Quinoline-3-Cboxylic Acid Pl-11; PANC3.27; ulifloxacin; Panc 03.27 Cells Line; 6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid; 6-fluoro-1-Methyl-4-oxo- 7-(1-piperazinyl)-4H-(1,3) S,N-containing heterocyclic bi- (3,2-a) quinoline-3-cboxylic acid; 6-FLUORO-1-METHYL-4-OXO-7-(1-PIPRAZINYL)-4H-(1,3)-THIAZETO(3,2-A)QUINOLINE-3-C; 6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-1H-[1,3]thiazeto[3,2-a]quinoline-3-cboxylic acid

物化性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 577.0±50.0 °C at 760 mmHg
• 分子式: C₁₆H₁₆FN₃O₃S
• 分子量: 349.38
• 闪点: 302.8±30.1 °C
• 精确质量: 349.089630
• PSA: 99.87000
• LogP: 1.31
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.725
• 储存条件: 2-8°C，干燥密封

生物活性

• 描述: Ulifloxacin 是一种广谱的喹诺酮抗生素 (antibiotic)。Ulifloxacin 是 Prulifloxacin (HY-B0024) 的活性代谢物。Ulifloxacin 具有抗菌活性。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Karageorgopoulos DE, et al. Antimicrobial activity of prulifloxacin in comparison with other fluoroquinolones against community-acquired urinary and respiratory pathogens isolated in Greece. Eur J Clin Microbiol Infect Dis. 2013 Nov;32(11):1417-22.

安全

• 海关编码: 2933990090

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海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
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Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%