3543-73-5

• 常用中文名：5-氨基-1-甲基-1H-苯并咪唑-2-丁酸乙酯
• 常用英文名：1-METHYL-5-AMINO-1H-BENZIMIDAZOLE-2-BUTANOIC ACID ETHYLESTER
• CAS号：3543-73-5
• 分子式：C₁₄H₁₉N₃O₂
• 分子量：261.320
• 发布时间：2018-12-28 08:09:59
• 更新时间：2026-07-04 16:03:58

名称

• 中文名: 5-氨基-1-甲基-1H-苯并咪唑-2-丁酸乙酯
• 英文名: ethyl 4-(5-amino-1-methylbenzimidazol-2-yl)butanoate
• 中文别名: 苯达莫司汀双去氯乙基乙酯; 1-甲基-5-氨基-1H-苯并咪唑-2-丁酸乙酯; 4-(1-甲基-5-氨基-1H-苯并咪唑-2-基)丁酸乙酯(盐酸苯达莫司汀中间体); [ 1-甲基-2- ( 4'-丁酸乙酯基) -5-硝基]-1H -苯并咪唑; 5-氨基-1-甲基-1H-苯并咪唑-2-丁酸乙酯 4; 5-氨基-1-甲基-1H-苯并咪唑-2-丁酸; 5-氨基-1-甲基-2-苯并咪唑基丁酸乙酯; 盐酸苯达莫司汀中间体1; 盐酸苯达莫斯汀中间体-3; 苯达莫斯汀中间体; [1-甲基-2-(4’-丁酸乙酯基)-5-硝基]-1H-苯并咪唑; 4-(1-甲基-5-氨基-1H-苯并咪唑-2-基)丁酸乙酯; 乙基 4-(5-氨基-1-甲基-1H-苯并[D]咪唑-2-基)丁酸酯; 1-甲基-5-氨基-1H-苯并咪唑-2-丁酸乙酯 CAS NO 3-5; 1-甲基-5-氨基-1H-苯并咪唑-2-丁酸乙酯(盐酸苯达莫司汀中间体); 苯达莫司汀盐酸盐杂质 标准品; 苯达莫斯汀杂质7; 1-甲基-5-氨基-1H-苯并咪唑-2-丁酸乙酯苯达莫司汀中间体; 盐酸苯达莫司汀/1-甲基-5-氨基-1H-苯并咪唑-2-丁酸乙酯; 盐酸苯达莫斯汀中间体; 苯达莫司汀杂质19
• 英文别名: Ethyl 5-amino-1-methyl-1H-benzimidazole-2-butanoate; ETHYL 4-(5-AMINO-1-METHYL-1HBENZIMIDAZOL-2-YL) BUTANOATE; 5-AMINO-1-METHYL-1H-BENZIMIDAZOLE-2-BUTANOIC ACID ETHYL ESTER; BendaMustine hydrochloride interMediate; 4-[5-Amino-1-MethylbenziMidazol-2-yl]butanoic acid ethyl ester; 1-Methyl-5-amino-1H-benzimidazole-2-butanoicacidethylester; 5-(5-amino-1-methyl-2-benzimidazolyl)-1-methoxy-2-pentanone; Ethyl-4-(5-amino-1-Methy-1H-benzo[d] iMidazol-2-yl)butanoate; 1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl ester; 4-(5-amino-1-methyl-1H-benzoimidazol-2-yl)-butyric acid ethyl ester; Bendamustine Hydrochloride Intermediate 3-5 API Manufacturer; ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate; 1-Methyl-5-amino-1H-benzimidazole-2; 5-Amino-1-Methyl; 1H-benzimidazol-1-methyl-5-amino-2-butanoic acid ethyl ester; 4-(5-amino-1-Methyl-1H-benzoiMidazol-2-yl)-butyric acid ethyl esterCAS; Ethyl 4-(5-amino-1-methyl-1H-benzimidazol-2-yl)butanoate; Ethyl4-(5-amino-1-methyl-1Hbenzo[d]imidazole -2-yl)butanoate; 1H-Benzimidazole-2-butanoic acid, 5-amino-1-methyl-, ethyl ester; 5-Amino-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester; 1-Methyl-5-amino-1H-benziMidazole-2-butanoic acid ethyl este; Bendamustine Intermediate; Ethyl 4-(5-amino-1-methyl-1H-1,3-benzimidazol-2-yl)butanoate; 4-(5-Amino-1-methyl-1H-benzoimidazol-2-yl)-butyric acidethylester; endamustine Dideschloroethyl Ethyl Ester; BendaMustine Dideschloroethyl Ethyl Ester; 4-(5-amino-1-methyl-1H-benzimidazol-2-yl)butanoate; 5-amino-1-methyl-2-Benzimidazolebutyric acid ethyl ester; Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butyrate; Bendamustine hydrochloride Intermediates 2; Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate; ethyl-4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl) butanoate; ethyl 4-(5-amino-1-Methyl-1H-1,3-benzodiazol-2-yl)butanoate

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 471.6±25.0 °C at 760 mmHg
• 熔点: 130-135ºC
• 分子式: C₁₄H₁₉N₃O₂
• 分子量: 261.320
• 闪点: 239.0±23.2 °C
• 精确质量: 261.147736
• PSA: 70.14000
• LogP: 1.72
• 外观性状: 棕色固体
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.591
• 储存条件: 室温，密封，干燥

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

3543-72-4 ~88% 3543-73-5

文献：US2014/31560 A1, ; Paragraph 0103; 0104; 0105; 0106 ;

369-36-8 ~% 3543-73-5

文献：US2014/31560 A1, ;

108-55-4 ~% 3543-73-5

文献：US2014/31560 A1, ;

31349-48-1 ~% 3543-73-5

文献：US2014/31560 A1, ;

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%