82854-37-3

• 常用中文名：松果菊苷
• 常用英文名：Echinacoside
• CAS号：82854-37-3
• 分子式：C₃₅H₄₆O₂₀
• 分子量：786.728
• 相关类别： 生物化工 植物提取物
• 发布时间：2018-08-22 17:19:17
• 更新时间：2026-07-01 10:38:21
• Echinacoside是一天然多酚化合物,具有广泛的医药活性,包括：抗氧化、抗炎症、神经保护、保肝等。

名称

• 中文名: 松果菊苷
• 英文名: [(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
• 中文别名: 松果菊苷(海胆苷,紫锥花苷,松果菊甙); 管花肉苁蓉; 肉苁蓉-松果菊苷; 海胆苷; 松果菊苷, 来源于肉苁蓉; (2R,3R,4R,5R,6R)-6-(3,4-二羟基苯乙氧基)-5-羟基-2-((((2R,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)甲基)-4-(((2S,3R,4R,5R,6S)-3,4,5-三羟基-6-甲基四氢-2H-吡喃-2-基)氧基)四氢-2H-吡喃-3-基 3-(3,4-二羟基苯基)丙烯酸酯; 海胆苷、紫锥花苷; 松果菊甙; 肉苁蓉松果菊; ECHINACOSIDE 松果菊苷; 肉苁蓉提取物 松果菊苷; 松果菊苷ECHINACOSIDE; 松果菊苷(1个月内); 松果菊苷-管花肉苁蓉提取物; 松果菊苷(海胆苷; 松果菊苷(对照品); 肉苁蓉提取物 (松果菊苷); 紫锥菊苷; 荒漠肉苁蓉粉; 紫锥花苷; 紫锥菊苷,海胆苷,松果菊甙; 松果菊苷(海胆苷)对照品; 海胆苷,紫锥花苷,松果菊甙; 松果菊苷 含量测定 可溯源; 松果菊苷,10 MM DMSO 溶液; 松果菊苷(分析标准品); 松果菊苷(标准品); 抑制剂Echinacoside; 松果菊
• 英文别名: (2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-3-yl (2E)-3-(3,4-dihydroxyphenyl)acrylate; Echinacoside/CH80711; Echinacea Purpurea Cichoric Acid; ECHINACOSIDE DESERTLIVING CISTANCHE P.E; Cistanche Deserticola Extract Echinacoside; Echinacoside from Cistanche deserticola Y.C.Ma; [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate; β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate]; Echinacoside, 10 mM in DMSO; ECHINACOSIDE(AMERICAN HERBAL PHMACOPOEIA); 2-(3,4-Dihydroxyphenyl)ethyl 6-deoxy-α-L-mannopyranosyl-(1->3)-[β-D-glucopyranosyl-(1->6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-β-D-glucopyranoside; 2-(3,4-dihydroxyphenyl)ethyl 6-deoxy-α-L-mannopyranosyl-(1-3)-[β-D-glucopyranosyl-(1-6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-β-D-glucopyranoside; 2-(3,4-Dihydroxyphenyl)ethyl-6-deoxy-α-L-mannopyranosyl-(1->3)-[β-D-glucopyranosyl-(1->6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-β-D-glucopyranoside; ECHINACOSIDE; (2R,3R,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-2-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl 3-(3,4-dihydroxyphenyl)acrylate; Echinacosidew; o-(beta-d-glucopyranosyl-)-,4-(3-(3,4-dihydroxyphenyl)-2-propenoat; Cistanche tubulosa extrac; UNII-I04O1DT48T; Cistanche tubulosa; Echinacoside/CH54339; 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-6-O-β-D-glucopyranosyl-4-O-[3-(3,4-dihydroxyphenyl)propenoyl]-β-D-glucopyranoside; Echinacoside Standd; Echinoside; ECHINACOSIDE(AHP); Echinacoside, froM Cistanche deserticola Y.C.Ma; Echinacoside [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl); 2-(3,4-Dihydroxyphenyl)ethyl 6-deoxy-α-L-mannopyranosyl-(1->3)-[β-D-glucopyranosyl-(1->6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-β-D-glucopyranoside; Echicoside; (2R,3R,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-2-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl 3-(3,4; beta-d-e; Purpureaside C; Echinacoside (P); 2-(3,4-dihydroxyphenyl)ethylo-6-deoxy-alpha-l-mannopyranosyl-glucopyranosid

物化性质

• 密度: 1.7±0.1 g/cm3
• 沸点: 1062.7±65.0 °C at 760 mmHg
• 分子式: C₃₅H₄₆O₂₀
• 分子量: 786.728
• 闪点: 327.9±27.8 °C
• 精确质量: 786.258240
• PSA: 324.44000
• LogP: 0.14
• 外观性状: 白色晶体
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.698
• 储存条件: 2-8°C

生物活性

• 描述: Echinacoside是一天然多酚化合物,具有广泛的医药活性,包括：抗氧化、抗炎症、神经保护、保肝等。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
  天然产物 >> 酚类
• 参考文献:

  [1]. Zhang D, et al. Echinacoside inhibits amyloid fibrillization of HEWL and protects against Aβ-induced neurotoxicity. Int J Biol Macromol. 2014 Sep 2;72C:243-253.

  [2]. Zhu M, et al. Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone. J Neurochem. 2013 Feb;124(4):571-80.

  [3]. Li F, et al. Antiosteoporotic activity of echinacoside in ovariectomized rats. Phytomedicine. 2013 Apr 15;20(6):549-57.

  [4]. Li F, et al. Echinacoside promotes bone regeneration by increasing OPG/RANKL ratio in MC3T3-E1 cells. Fitoterapia. 2012 Dec;83(8):1443-50.

  [5]. Li X, et al. Echinacoside ameliorates D-galactosamine plus lipopolysaccharide-induced acute liver injury in mice via inhibition of apoptosis and inflammation. Scand J Gastroenterol. 2014 Aug;49(8):993-1000.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : LZ5786500 CHEMICAL NAME : Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-alpha-L-mannopyranosyl-(1-3)- O-(beta-D-glucopyranosyl-(1-6))-, 4-(3-(3,4-dihydroxyphenyl)-2-propenoate), beta-D- CAS REGISTRY NUMBER : 82854-37-3 LAST UPDATED : 198910 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C35-H40-O20 MOLECULAR WEIGHT : 780.75 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 140 mg/kg SEX/DURATION : male 14 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - other effects on male REFERENCE : YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 105,1131,1985

安全

• 危害码 (欧洲): T+
• 安全声明 (欧洲): 24/25
• 危险品运输编码: NONH for all modes of transport
• RTECS号: LZ5786500