182127-92-0

• 常用中文名：2-巯基-6-甲基-4-(三氟甲基)烟腈
• 常用英文名：2-MERCAPTO-6-METHYL-4-(TRIFLUOROMETHYL)NICOTINONITRILE
• CAS号：182127-92-0
• 分子式：C₈H₅F₃N₂S
• 分子量：218.19900
• 发布时间：2018-07-06 17:15:33
• 更新时间：2024-01-10 10:52:46

名称

• 中文名: 2-巯基-6-甲基-4-(三氟甲基)烟腈
• 英文名: 6-methyl-2-sulfanylidene-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile

物化性质

• 密度: 1.44g/cm3
• 沸点: 204.4ºC at 760mmHg
• 熔点: 200ºC
• 分子式: C₈H₅F₃N₂S
• 分子量: 218.19900
• 闪点: 77.4ºC
• 精确质量: 218.01300
• PSA: 75.48000
• LogP: 2.56918
• 蒸汽压: 0.263mmHg at 25°C
• 折射率: 1.536

MSDS

Name: 2-Mercapto-6-methyl-4-(trifluoromethyl)nicotinonitrile 97% Material Safety Data Sheet Synonym: CAS: 182127-92-0 Section 1 - Chemical Product MSDS Name:2-Mercapto-6-methyl-4-(trifluoromethyl)nicotinonitrile 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 182127-92-0 2-Mercapto-6-methyl-4-(trifluoromethyl 97% unlisted Hazard Symbols: XN Risk Phrases: 20/21/22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Harmful if inhaled. May cause respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 182127-92-0: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: Not available. Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 214 - 217 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C8H5F3N2S Molecular Weight: 218.2 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen cyanide, nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide, fluorine, hydrogen fluoride gas. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 182127-92-0 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-Mercapto-6-methyl-4-(trifluoromethyl)nicotinonitrile - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: NITRILES, SOLID, TOXIC, N.O.S.* Hazard Class: 6.1 UN Number: 3276 Packing Group: III IMO Shipping Name: NITRILES, TOXIC, N.O.S. Hazard Class: 6.1 UN Number: 3276 Packing Group: III RID/ADR Shipping Name: NITRILES, TOXIC, N.O.S. Hazard Class: 6.1 UN Number: 3276 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. Safety Phrases: S 36/37 Wear suitable protective clothing and gloves. WGK (Water Danger/Protection) CAS# 182127-92-0: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 182127-92-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 182127-92-0 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xn:Harmful;
• 风险声明 (欧洲): R20/21/22
• 安全声明 (欧洲): S36/37
• 海关编码: 2933399090

合成路线

7357-70-2 367-57-7 ~87% 182127-92-0

文献：Nikishin; Kislyi; Nesterov; Shestopalov; Struchkov; Semenov Russian Chemical Bulletin, 1998 , vol. 47, # 3 p. 465 - 468

7357-70-2 144864-94-8 ~90% 182127-92-0

文献：Kislyi, Victor P.; Nikishin, Kirill G.; Kruglova, Elena Ya.; Shestopalov, Alexandr M.; Semenov, Victor V.; Gakh, Andrei A.; Buchanan III Tetrahedron, 1996 , vol. 52, # 33 p. 10841 - 10848

7357-70-2 234112-44-8 ~% 182127-92-0

文献：Kislyi, Victor P.; Nikishin, Kirill G.; Kruglova, Elena Ya.; Shestopalov, Alexandr M.; Semenov, Victor V.; Gakh, Andrei A.; Buchanan III Tetrahedron, 1996 , vol. 52, # 33 p. 10841 - 10848

7357-70-2 135351-20-1 ~% 182127-92-0

文献：Nikishin; Kislyi; Nesterov; Shestopalov; Struchkov; Semenov Russian Chemical Bulletin, 1998 , vol. 47, # 3 p. 465 - 468

上下游产品

上游产品  4
7357-70-2 367-57-7 234112-44-8 135351-20-1
下游产品  0

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%