1847-58-1

• 常用中文名：鱼腥草素纳
• 常用英文名：Sodium houttuyfonate
• CAS号：1847-58-1
• 分子式：C₁₄H₂₇NaO₅S
• 分子量：330.416
• 相关类别： 研究领域 炎症/免疫
• 发布时间：2018-07-05 23:06:34
• 更新时间：2024-01-02 21:17:17
• Sodium lauryl sulfoacetate 是一种植物来源的固体阴离子表面活性剂。Sodium lauryl sulfoacetate 是一种免疫佐剂,具有抗免疫抑制作用。

名称

• 中文名: 月桂醇磺基乙酸酯钠盐
• 英文名: Sodium new houttuyfonate
• 中文别名: 磺化乙酸十二烷基酯钠; 新鱼腥草素钠; 鱼腥草素钠
• 英文别名: Dodecyloxycarbonylmethanesulfonic acid sodium salt; Dodecyl sodium sulfoacetate; Sodium lauryl sulfoacetate; Acetic acid, 2-sulfo-, dodecyl ester, sodium salt (1:1); Sodium 2-(dodecyloxy)-2-oxoethanesulfonate; 2-Sulfoacetic acid dodecyl ester sodium salt

物化性质

• 分子式: C₁₄H₂₇NaO₅S
• 分子量: 330.416
• 精确质量: 330.147675
• PSA: 91.88000
• LogP: 4.07650
• 外观性状: 粉末
• 储存条件: 2-8C
• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:0

  3.氢键受体数量:5

  4.可旋转化学键数量:14

  5.互变异构体数量:无

  6.拓扑分子极性表面积91.9

  7.重原子数量:21

  8.表面电荷:0

  9.复杂度:338

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:2

生物活性

• 描述: Sodium lauryl sulfoacetate 是一种植物来源的固体阴离子表面活性剂。Sodium lauryl sulfoacetate 是一种免疫佐剂,具有抗免疫抑制作用。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Tiffany Ann Renninger. Encapsulated dehydrated shampoo comprising sodium lauryl sulfoacetate. US10357095B1.

  [2]. Cheng D, et al. The immune enhancement of sodium lauryl sulfoacetate in chickens. Vet Med Int. 2010;2010:485060.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AJ4930000 CHEMICAL NAME : Acetic acid, sulfo-, 1-dodecyl ester, sodium salt CAS REGISTRY NUMBER : 1847-58-1 LAST UPDATED : 199701 DATA ITEMS CITED : 8 MOLECULAR FORMULA : C14-H27-O5-S.Na MOLECULAR WEIGHT : 330.46 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit REFERENCE : JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(3),261,1987 TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit REFERENCE : JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(3),261,1987 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 700 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(3),261,1987 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 980 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JADSAY Journal of the American Dental Association. (American Dental Assoc., 211 E. Chicago Ave., Chicago, IL 60611) V.9- 1922- Volume(issue)/page/year: 26,1461,1939 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 22400 mg/kg/28D-I TOXIC EFFECTS : Brain and Coverings - changes in brain weight Kidney, Ureter, Bladder - changes in bladder weight REFERENCE : JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(3),261,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83141 No. of Facilities: 47 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 990 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83141 No. of Facilities: 304 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 3648 (estimated) No. of Female Employees: 3648 (estimated)

安全

• 海关编码: 2914509090

合成路线

3674-07-5 ~% 1847-58-1

文献：Monatshefte fur Chemie, , vol. 128, # 11 p. 1085 - 1092

112-53-8 ~% 1847-58-1

文献：Monatshefte fur Chemie, , vol. 128, # 11 p. 1085 - 1092

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3674-07-5 112-53-8
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海关

海关编码	2914509090
中文概述	2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 丙酮报明包装
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%