5028-17-1

• 常用中文名：2-(4-甲基哌嗪)-3-氨基吡啶
• 常用英文名：2-(4-Methylpiperazin-1-yl)pyridin-3-amine
• CAS号：5028-17-1
• 分子式：C₁₀H₁₆N₄
• 分子量：192.261
• 发布时间：2018-12-28 13:37:19
• 更新时间：2024-01-23 14:23:53

名称

• 中文名: 2-(4-甲基哌嗪)-3-氨基吡啶
• 英文名: 2-(4-methylpiperazin-1-yl)pyridin-3-amine
• 英文别名: 4-Methyl-1-(3-amino-2-pyridyl)piperazine; 2-(4-methylpiperazin-1-yl)pyridin-3-amine; 2-(4-methyl-piperazin-1-yl)-pyridin-3-ylamine; 3-Amino-2-(4-methyl-1-piperazinyl)-pyridin; 1-(3-Amino-2-pyridyl)-4-methylpiperazine; 1-Methyl-4-(3-aminopyrid-2-yl)-piperazin; 3-Pyridinamine, 2-(4-methyl-1-piperazinyl)-; 2-(3',4'-DIBENZYLOXY-PHENYL)MORPHOLINE; 2-(4-Methyl-1-piperazinyl)-3-pyridinamine; Piperazine,1-(3-amino-2-pyridyl)-4-methyl

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 361.6±42.0 °C at 760 mmHg
• 熔点: 112-114ºC
• 分子式: C₁₀H₁₆N₄
• 分子量: 192.261
• 闪点: 172.5±27.9 °C
• 精确质量: 192.137497
• PSA: 45.39000
• LogP: 0.14
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.594
• 储存条件: 2-8°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TK8113500 CHEMICAL NAME : Piperazine, 1-(3-amino-2-pyridyl)-4-methyl- CAS REGISTRY NUMBER : 5028-17-1 BEILSTEIN REFERENCE NO. : 0613365 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C10-H16-N4 MOLECULAR WEIGHT : 192.30 WISWESSER LINE NOTATION : T6N DNTJ A1 D- BT6NJ CZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - excitement REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,812,1967

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

5028-15-9 ~78% 5028-17-1

文献：PFIZER PRODUCTS INC. Patent: WO2006/48727 A1, 2006 ; Location in patent: Page/Page column 72-73 ; WO 2006/048727 A1

220499-48-9 ~70% 5028-17-1

文献：Dunn Organic Preparations and Procedures International, 1998 , vol. 30, # 6 p. 709 - 713

109-01-3 ~% 5028-17-1

文献：Dunn Organic Preparations and Procedures International, 1998 , vol. 30, # 6 p. 709 - 713

39856-57-0 ~% 5028-17-1

文献：Dunn Organic Preparations and Procedures International, 1998 , vol. 30, # 6 p. 709 - 713

109-01-3 5470-18-8 ~% 5028-17-1

文献：SAMUMED, LLC; HOOD, John; KC, Sunil Kumar Patent: WO2013/40215 A1, 2013 ;

109-01-3 6298-19-7 ~72% 5028-17-1

文献：Dunn Organic Preparations and Procedures International, 1998 , vol. 30, # 6 p. 709 - 713

上下游产品

上游产品  5
5028-15-9 109-01-3 39856-57-0 5470-18-8
6298-19-7
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%