4613-62-1

4613-62-1结构式

常用中文名：3-脱氧-1,2:5,6-双-O-(1-甲基亚乙基)-Α-D-核六呋喃糖
常用英文名：a-D-ribo-Hexofuranose,3-deoxy-1,2:5,6-bis-O-(1-methylethylidene)
CAS号：4613-62-1
分子式：C₁₂H₂₀O₅
分子量：244.28
相关类别：信号通路细胞周期/DNA损伤核苷抗代谢药/类似物
发布时间：2017-10-26 05:59:57
更新时间：2026-07-02 15:39:53
3-脱氧-1,2:5,6-双-O-(1-甲基亚乙基)-α-D-核糖-外呋喃糖是嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性,靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制DNA合成、诱导细胞凋亡等[1]。

中文名	3-脱氧-1,2:5,6-双-O-(1-甲基亚乙基)-Α-D-核六呋喃糖
英文名	5-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole
中文别名	1,2:5,6-二-O-异丙亚基-3-脱氧-ALPHA-D-核-呋喃己糖 3-脱氧-1,2:5,6-双-O-(1-甲基亚乙基)-Α-D-核-呋喃己糖 3-脱氧-1,2:5,6-O-双异丙叉-Α-D-呋喃葡萄糖
英文别名	3-Deoxy-1,2:5,6-di-O-isopropylidene-alpha-D-glucose a-D-ribo-Hexofuranose, 3-deoxy-1,2:5,6-bis-O-(1-Methylethylidene) 1-O,2-O:5-O,6-O-Diisopropylidene-3-deoxy-α-D-glucofuranose α-D-ribo-Hexofuranose, 3-deoxy-1,2:5,6-bis-O-(1-methylethylidene) 1-O,2-O:5-O,6-O-Diisopropylidene-3-deoxy-α-D-allofuranose 3-Deoxy-1,2 3-(2,2-dimethyl-1,3-dioxolan-4-yl)-7,7-dimethyl-2,6,8-trioxabicyclo[3.3.0]octane 1,2:5,6-Di-O-Isopropylidene-3-deoxy-D-ribo-hexofuranose 1-O,2-O:5-O,6-O-Bis(isopropylidene)-3-deoxy-α-D-ribo-hexofuranose 5,6-di-O-isopropylidene-D-glucofuranose (3,5S,6-5-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole 5-(2,2-Dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole a-D-Ribo-hexafuranose,3-deoxy-1,2:5,6-bis-O-(1-methylethylidene) 3-Deoxy-1,2:5,6-di-O-isopropylidene-alpha-D-glucofuranose 1,2:5,6-Di-O-isopropylidene-3-deoxy-alpha-D-ribo-hexofuranose 3-Deoxy-1,2:5,6-di-O-isopropylidene-D-glucose 3-Deoxy-1,2:5,6-bis-O-(1-methylethylidene)-α-D-ribo-hexofuranose

描述	3-脱氧-1,2:5,6-双-O-(1-甲基亚乙基)-α-D-核糖-外呋喃糖是嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性,靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制DNA合成、诱导细胞凋亡等[1]。
相关类别	研究领域 >> 癌症信号通路 >> 细胞周期/DNA损伤 >> 核苷抗代谢药/类似物
参考文献	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.