21740-23-8

• 常用中文名：1-氯-3,5-二-(对氯苯甲酰基)-2-脱氧-D-呋喃核糖
• 常用英文名：1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose
• CAS号：21740-23-8
• 分子式：C₁₉H₁₅Cl₃O₅
• 分子量：429.678
• 发布时间：2018-08-15 12:49:04
• 更新时间：2026-06-30 21:43:29

名称

• 中文名: 1-氯-2-脱氧-3,5-二-O-对氯苯甲酰基-D-核糖
• 英文名: [(2S,3R,5R)-5-chloro-3-(4-chlorobenzoyl)oxyoxolan-2-yl]methyl 4-chlorobenzoate
• 中文别名: 1-氯-2-脱氧-3,5-二-氧-对氯苯甲酰基-D-呋喃核糖; 1-氯-2-脱氧-3,5-氧-二对氯苯甲酰基-D-核糖; 1-氯-2-脱氧-3,5-二-O-对氯苯甲酰基; 1-氯-3,5-二对氯苯甲酰基-2-脱氧-D-核糖; (2R,3S,5R)-5-氯-2-(((4-氯苯甲酰)氧基)甲基)四氢呋喃-3-基4-氯苯甲酸酯; 3,5二- O-(对氯苯甲酰)-2 -脱氧-Α-的D -呋喃核糖氯; 1-Α-氯-2-脱氧-3,5-二-O-对氯苯甲酰基-D-核糖; 1-氯-2-脱氧-3,5-二-O- 对氯苯甲酰基-Α-D-核糖; 3,5二-O-(对氯苯甲酰)-2-脱氧-Α-的D-呋喃核糖氯; 1-氯-3,5-二-(对氯苯甲酰基)-2-脱氧-呋喃核糖; (2S,3R,5R)-5-氯-2-(((4-氯苯甲酰)氧基)甲基)四氢呋喃-3-基4-氯苯甲酸酯; 1-氯-3,5-二对氯苯甲酰氧基-2-脱氧-D-呋喃核糖; 3,5-二- O-(对氯苯甲酰)-2 -脱氧-Α-的D -呋喃核糖氯; 氧基-2-脱氧-D-核糖; 对氯氯化物 地西他滨中间体; 2-脱氧-3,5-二-O-(4-氯苯甲酰基)-ALPHA-D-呋喃核糖基氯; 1-氯-2-脱氧-3,5-O-二(4-氯苯甲酰基)-ALPHA-D-赤式-呋喃戊糖; 1-氯-2-脱氧-3,5-二对氯苯甲酰基-D-核糖; 1-氯-2-脱氧-3,5-二-O-对氯苯甲酰基-D-核; 1-氯-2-脱氧-3,5-二-O- 对氯苯甲酰基-D-核; 氯-3,5-二对氯苯甲酰基-2-脱氧-D-核糖; 地西他滨N-2中间体:(4S,5R)-2-氯-4-苯甲酰氧基-5-(苯甲酰氧甲基)四氢呋喃; 3,5-二- O-(对氯苯甲酰)-2 -脱氧-Α-的D -呋喃核糖氯/21-8; 1-氯-2-脱氧-3,5-二-O-对氯苯甲酰基-D-核糖(氯糖); 曲氟尿苷FTD-SM2; (2R,3S,5R)-5-氯-2-(((4-氯苯甲酰基)氧基)甲基)四氢呋喃-3-基4-氯苯甲酸酯; 1-氯-3,5-二对氯苯甲酰基-2-脱氧核糖; 1-a-氯-3,5-二-O-对氯苯甲酰基-2-脱氧-D-呋喃核糖; 氯酰糖
• 英文别名: 1-Chloro-3,5-bis-(4-chlorobenzoyl)-2-deoxy-D-ribofuranose; (4S,5R)-2-chloro-4-benzoyloxy-5-(benzoyloxymethyl)tetrahydrofuran; 3,5-Di-O-(p-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl Chloride; 3,5-O-Bis(p-chlorobenzoyl)-2-deoxy-alpha-D-ribofuranosyl chloride; D-erythro-Pentofuranosyl chloride, 2-deoxy-, bis(4-chlorobenzoate); [5-chloro-3-(4-chlorobenzoyl)oxyoxolan-2-yl]methyl 4-chlorobenzoate; 2-deoxy-α-D-erythro-Pentofuranosyl chloride 3,5-bis(4-chlorobenzoate); 1-(3,5-di-O-(4-chlorobenzoyl) -2-deoxy-alpha-D-ribofuranosyl) chloride; 3,5-di-O-(p-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl chloride; 3,5-Bis(4-chlorobenzoyl)-2-deoxy-.alpha.-D-ribofuranosyl Chloride; 1-α-Chloro-3,5-di-O-(4-chlorobenzoyl) -2-deoxy-D-ribofuranose; 1-Chloro-3,5-Di-(P-Chlorobenzoyl)-2-Deoxy-D-Ribose; (2R,3S,5R)-5-Chloro-2-(((4-chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate; 3,5-O-bis(p-chlorobenzoyl)-2-deoxy-α-D; Pentofuranosyl chloride, 2-deoxy-, bis(4-chlorobenzoate); 1-Cl-3,5-bis-(4-cl-bz)- 2-deoxy-D-ribofuranose; Chloride sug; chlorobenzoyl)-2-deoxy-D-ribose; 2-Deoxy-alpha-D-erythro-pentofuranosyl chloride 3,5-bis(4-chlorobenzoate); 2-Deoxy-3,5-di-O-(4-chlorobenzoyl)-alpha-D-ribofuranosyl Chloride; [5-Chloro-2-[(4-chlorobenzoyl)oxymethyl]oxolan-3-yl] 4-chlorobenzoate; Chloro sug; 3,5-O-Bis(p-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl chloride; (2R,3S,4R,5R)-5-Chloro-2-((4-chlorobenzoyloxy)methyl)-4-hydroxytetrahydrofuran-3-yl 4-chlorobenzoate; 1-a-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose; Oxygen-2-deoxy-D-ribose; [(2R,3S,4R,5R)-5-chloro-3-[(4-chlorophenyl)cbonyloxy]-4-hydroxyoxolan-2-yl]Methyl 4-chlorobenzoate; 3,5-Bis-O-(4-chlorobenzoyl)-2-deoxypentofuranosyl chloride; "3,5-Di-O-(p-chlorobenzoyl)-2-deoxy-a-D-ribofuranosyl Chloride"; 1-Chloro-2-deoxy-3,5-O-bis(p-chlorobenzoyl)-α-D-erythro-pentofuranose; 1-Chloro-3,5-di-O-(4-chlorobenzoyl)-2-deoxy-a-D-ribofuranose; 3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-D-erythro-pentofuranosyl chloride; a-D-erythro-Pentofuranosylchloride, 2-deoxy-, 3,5-bis(4-chlorobenzoate); (2S,3R,5R)-5-Chloro-2-(((4-chlorobenzoyl)oxy)-methyl)tetrahydrofuran-3-yl 4-chlorobenzoate; 3,5-bis[o-(p-chlorbenzoyl)]-alpha-D-ribofuranosyl chloride; (2S,3R,5R)-5-Chloro-2-(((4-chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate; Trifluridine intermediate; 1-Chloro-2-deoxy-3,5-O-bis(4-chlorobenzoyl)-alpha-D-erythro-pentofuranose; α-D-erythro-Pentofuranosyl chloride, 2-deoxy-, 3,5-bis(4-chlorobenzoate); 1-Chloro-3,5-di-(p-chlorobenzoyl)-2-deoxy-ribofuranose

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 530.6±50.0 °C at 760 mmHg
• 熔点: 110-118ºC (dec.)
• 分子式: C₁₉H₁₅Cl₃O₅
• 分子量: 429.678
• 闪点: 193.1±29.1 °C
• 精确质量: 427.998505
• PSA: 61.83000
• LogP: 5.44
• 外观性状: 白色固体
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.610
• 储存条件: 2-8°C

合成路线

80339-59-9 ~78% 21740-23-8

文献：Albemarle Corporation Patent: US2010/249394 A1, 2010 ; Location in patent: Page/Page column 4-5 ;

452-51-7 122-01-0 ~79% 21740-23-8

文献：Wang; Duan; Wiebe; Balzarini; De Clercq; Knaus Nucleosides, Nucleotides and Nucleic Acids, 2001 , vol. 20, # 1-2 p. 11 - 40

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