1034301-08-0

• 常用中文名：3',5'-二对氯苯甲酰氧基-2-脱氧-5-氮杂胞苷
• 常用英文名：3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine
• CAS号：1034301-08-0
• 分子式：C₂₂H₁₈Cl₂N₄O₆
• 分子量：505.307
• 发布时间：2016-11-11 01:39:16
• 更新时间：2026-07-09 19:10:47

名称

• 中文名: 3',5'-二对氯苯甲酰氧基-2-脱氧-5-氮杂胞苷
• 英文名: [(2R,3S,5S)-5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-3-(4-chlorobenzoyl)oxyoxolan-2-yl]methyl 4-chlorobenzoate
• 中文别名: 地西他滨中间体CR; 地西他滨RC B; DECITABINE相关物质B; 地西他滨杂质CR; 4-氨基-1- [3,5-二-O-(4-氯苯甲酰基)-2-脱氧Β-D赤式 - 呋喃戊糖基] -1,3,5-三嗪-2(1H) - 酮; 地西他滨中间体N-1; 地西他滨中间体; 地西他滨杂质2(地西他滨杂质B); 地西他滨相关化合物B; 地西他滨中间体,3',5'-二对氯苯甲酰氧基-2-脱氧-5-氮 杂胞苷; 地西他滨杂质36; 4-氨基-1-[3,5-双-O-(4-氯苯甲酰基)-2-脱氧-Β-D-赤-五呋喃糖基]-1,3,5-三嗪-2(1H); 3‘,5‘-二对氯苯甲 酰脱氧- 5-氮杂胞昔
• 英文别名: 3',5'-di-o-p-chlorobenzoy -deoxy-5-azacytosine; 3 ', 5' - Dichlorobenzoyl oxy-2-deoxy-5-azacytidine; Decitabine Impurity 2（Decitabine Related Compound B）; β-Decitabine-3'',5''-bis(4-chlorobenzoate); Decitabine RC B; 1,3,5-Triazin-2(1H)-one, 4-amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]; 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-beta-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one; 3',5'- di-p-chlorobenzoyloxy -2- deoxy -5- azacytidine; Decitabine Impurity 36; 3',5'-Bis-O-(4-chlorobenzoyl)-2-deoxy-5-azacytosine 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-beta-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one; 3 ', 5' - Dichlorobenzoyloxy-2-deoxy-5-azacytidine; 3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine ISO 9001：2015 REACH; Decitabine Intermediate CR; Decitabine Impurity 2(Decitabine RC B); Decitabine Related Compound B; (2R,3S,5R)-5-(4-Amino-2-oxo-1,3,5-triazin-1(2H)-yl)-2-(((4-chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate; 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one; 1,3,5-Triazin-2(1H)-one,4-amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-b-D-erythro-pentofuranosyl]; 3',5'-di-o-p-chlorobenzoy I-2-deoxy-5-azacytosine; Decitabine impurity 6/(2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-2-(((4-chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate; 3',5'-Bis-O-(4-chlorobenzoyl)-2-deoxy-5-azacytosine

物化性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 642.6±65.0 °C at 760 mmHg
• 分子式: C₂₂H₁₈Cl₂N₄O₆
• 分子量: 505.307
• 闪点: 342.4±34.3 °C
• 精确质量: 504.060333
• PSA: 136.62000
• LogP: 3.85
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.687
• 储存条件: 室温

安全

• 危害码 (欧洲): Xn

合成路线

21740-23-8 52523-35-0 ~% 1034301-08-0

文献：EP2050757 A1, ; Page/Page column 3-4 ;

21740-23-8 52523-35-0 ~% 1034301-08-0 1140891-02-6

文献：US2010/249394 A1, ; Page/Page column 5 ;

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