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| 中文名 | N-叔丁氧羰基-D-亮氨酸 |
|---|---|
| 英文名 | N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-leucine hydrate (1:1) |
| 中文别名 |
N-Boc-D-亮氨酸一水合物
BOC-D-亮氨酸 |
| 英文别名 |
BOC-D-Leucinemonohydrate
Boc-D-Leu-OH&BOC-D-LEU N-BOC-D-Leucine.H2O Boc-D-Leu-OH Hydrate N-(tert-Butoxycarbonyl)-D-leucine D-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-, hydrate (1:1) BOC-D-LEUCINE-OH N-T-BOC-D-LEUCINE Boc-D-Leu-OH N-(tert-Butoxycarbonyl)-D-leucine hydrate (1:1) N-(tert-Butoxycarbonyl)-D-leucine Hydrate BOC-D-LEU-OH2O N-tert-butoxycarbonyl-D-leucine n-boc-d-leucine N-Boc-D-leucine Hydrate D-Leucine, N-[(1,1-dimethylethoxy)carbonyl]- tert-butoxycarbonyl-D-leucine N-(t-butyloxycarbonyl)-D-leucine N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-leucine hydrate (1:1) Boc-D-Leu-OH.H2O N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-leucine BOC-D-LEUCINE Boc-(R)-leucine Boc-D-Leucine hydrate Boc-D-Leu-OH·H2O |
| 描述 | Boc-D-亮氨酸一水合物(Boc-D-Leu-OH水合物)是D-亮酸(L330150)的N-Boc-保护形式。D-亮氨酸是L-亮氨酸(L330110)的非天然异构体,作为乳酸链球菌的自动抑制剂。D-亮氨酸显示出强大的抗癫痫作用[1]。 |
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| 相关类别 | |
| 参考文献 |
[1]. Hartman AL, et al. Potent anti-seizure effects of D-leucine. Neurobiol Dis. 2015 Oct;82:46-53. |
| 密度 | 1.1±0.1 g/cm3 |
|---|---|
| 沸点 | 356.0±25.0 °C at 760 mmHg |
| 熔点 | 88 °C |
| 分子式 | C11H21NO4 |
| 分子量 | 231.289 |
| 闪点 | 169.1±23.2 °C |
| 精确质量 | 231.147064 |
| PSA | 88.35000 |
| LogP | 2.51 |
| 外观性状 | 固体;White to Almost white powder to crystal |
| 蒸汽压 | 0.0±1.7 mmHg at 25°C |
| 折射率 | 1.461 |
| 储存条件 | Store below +30°C. |
| 水溶解性 | 可溶于：甲醇 |
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Material Safety Data Sheet
Section1. Identification of the substance Product Name: Boc-D-Leu-OH H2O Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:Boc-D-Leu-OH H2O CAS number:200937-17-3 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels, refrigerated. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C11H21NO4.H2O Molecular weight:249.3 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A |