51247-07-5

• 常用中文名：[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate
• 常用英文名：[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate
• CAS号：51247-07-5
• 分子式：C₁₂H₁₅FN₂O₅
• 分子量：286.25600
• 发布时间：2016-09-15 09:27:56
• 更新时间：2024-01-05 13:47:53

名称

• 英文名: [(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate
• 英文别名: 5'-O-acetyl-FLT; Thymidine,3'-deoxy-3'-fluoro-,5'-acetate; 5'-O-Acetyl-3'-deoxy-3'-fluorothymidine; 3'-Deoxy-3'-fluoro-5'-O-acetylthymidine; 3'-Fluoro-3'-deoxythymidine acetate; 5'-O-Acetyl-3'-desoxy-3'-fluor-thymidin; Acetyl-FLT; O5'-acetyl-3'-fluoro-3'-deoxy-thymidine

物化性质

• 密度: 1.38g/cm3
• 分子式: C₁₂H₁₅FN₂O₅
• 分子量: 286.25600
• 精确质量: 286.09600
• PSA: 90.65000
• LogP: 0.44600
• 折射率: 1.536

合成路线

108-24-7 51247-06-4 ~58% 51247-07-5

文献：Huang; Chen; Wang; Kim; Warshaw; Armstrong; Zhu; Chou; Watanabe; Matulic-Adamic; Su; Fox; Polsky; Baron; Gold; Hardy; Zuckerman Journal of Medicinal Chemistry, 1991 , vol. 34, # 5 p. 1640 - 1646

135197-62-5 ~70% 51247-07-5

文献：Green; Blum Tetrahedron Letters, 1991 , vol. 32, # 19 p. 2091 - 2094

146457-58-1 7288-28-0 ~% 120713-85-1 51247-07-5

文献：Hager, Michael W.; Liotta, Dennis C. Tetrahedron Letters, 1992 , vol. 33, # 47 p. 7083 - 7086

15981-86-9 ~% 51247-07-5

文献：Huang; Chen; Wang; Kim; Warshaw; Armstrong; Zhu; Chou; Watanabe; Matulic-Adamic; Su; Fox; Polsky; Baron; Gold; Hardy; Zuckerman Journal of Medicinal Chemistry, 1991 , vol. 34, # 5 p. 1640 - 1646