57653-85-7

• 常用中文名：1,2,3,6,7,8-六氯二苯并-对-二恶英
• 常用英文名：1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin
• CAS号：57653-85-7
• 分子式：C₁₂H₂Cl₆O₂
• 分子量：390.86100
• 发布时间：2018-12-24 08:20:12
• 更新时间：2025-08-31 20:39:25

名称

• 中文名: 1,2,3,6,7,8-六氯二苯并-对-二恶英
• 英文名: 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin
• 英文别名: 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin

物化性质

• 密度: 1.777 g/cm3
• 沸点: 478ºC at 760 mmHg
• 熔点: 285-286ºC
• 分子式: C₁₂H₂Cl₆O₂
• 分子量: 390.86100
• 闪点: 182.9ºC
• 精确质量: 387.81900
• PSA: 18.46000
• LogP: 7.50500

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : HP3280100 CHEMICAL NAME : Dibenzo-p-dioxin, 1,2,3,6,7,8-hexachloro- CAS REGISTRY NUMBER : 57653-85-7 BEILSTEIN REFERENCE NO. : 1627652 LAST UPDATED : 199806 DATA ITEMS CITED : 9 MOLECULAR FORMULA : C12-H2-Cl6-O2 MOLECULAR WEIGHT : 390.84 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1250 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 70 ug/kg TOXIC EFFECTS : Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 140 ug/kg/14D-C TOXIC EFFECTS : Immunological Including Allergic - decrease in humoral immune response MUTATION DATA TYPE OF TEST : Morphological transformation TEST SYSTEM : Rodent - mouse Fibroblast DOSE/DURATION : 400 pmol/L REFERENCE : CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 8,1485,1987 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 69,33,1997

安全

• 危险品运输编码: UN 2811
• 包装等级: I
• 危险类别: 6.1(a)

合成路线

108-90-7 ~% 57653-85-7

文献：Environmental Science and Technology, , vol. 38, # 19 p. 5217 - 5223

127-18-4 ~% 57653-85-7

文献：Environmental Science and Technology, , vol. 37, # 15 p. 3323 - 3331

95-95-4 ~% 40321-76-4 57653-85-7 39227-28-6 详细

文献：Chemosphere, , vol. 45, # 2 p. 129 - 136

58200-74-1 ~% 19408-74-3 57653-85-7

文献：Analytical Chemistry, , vol. 56, # 3 p. 442 - 448

88211-73-8 ~% 58200-69-4 57653-85-7 64461-98-9 详细

文献：Analytical Chemistry, , vol. 56, # 3 p. 442 - 448