57653-85-7

57653-85-7 structure
57653-85-7 structure
  • Name: 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin
  • Chemical Name: 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin
  • CAS Number: 57653-85-7
  • Molecular Formula: C12H2Cl6O2
  • Molecular Weight: 390.86100
  • Create Date: 2018-12-24 08:20:12
  • Modify Date: 2024-01-11 22:50:17

Name 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin
Synonyms 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin
Density 1.777 g/cm3
Boiling Point 478ºC at 760 mmHg
Melting Point 285-286ºC
Molecular Formula C12H2Cl6O2
Molecular Weight 390.86100
Flash Point 182.9ºC
Exact Mass 387.81900
PSA 18.46000
LogP 7.50500

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HP3280100
CHEMICAL NAME :
Dibenzo-p-dioxin, 1,2,3,6,7,8-hexachloro-
CAS REGISTRY NUMBER :
57653-85-7
BEILSTEIN REFERENCE NO. :
1627652
LAST UPDATED :
199806
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C12-H2-Cl6-O2
MOLECULAR WEIGHT :
390.84

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
70 ug/kg
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
140 ug/kg/14D-C
TOXIC EFFECTS :
Immunological Including Allergic - decrease in humoral immune response

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - mouse Fibroblast
DOSE/DURATION :
400 pmol/L
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 8,1485,1987 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 69,33,1997
RIDADR UN 2811
Packaging Group I
Hazard Class 6.1(a)