160201-86-5

• 常用中文名：(PHE13,TYR19)-MCH (HUMAN,MOUSE,RAT)
• 常用英文名：(Phe13,Tyr19)-MCH (human, mouse, rat)
• CAS号：160201-86-5
• 分子式：C₁₀₉H₁₆₀N₃₀O₂₆S₄
• 分子量：2434.88000
• 相关类别： 信号通路 G 蛋白偶联受体/G 蛋白 MCHR1(GPR24)
• 发布时间：2018-11-24 18:26:13
• 更新时间：2026-07-02 22:30:22
• (Phe13,Tyr19)-MCH(人、小鼠、大鼠)是一种有效的SLC-1和S643b受体配体。(Phe13,Tyr19)-MCH(人、小鼠、大鼠)可用作SLC-1和S643b受体的激动剂[1]。

名称

• 中文名: (PHE13,TYR19)-MCH (HUMAN,MOUSE,RAT)
• 英文名: [Phe13,Tyr19]-MCH (human, mouse, rat)
• 中文别名: ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-PHE-ARG-PRO-CYS-TRP-GLN-TYR; (PHE13,TYR19)-MELANIN-CONCENTRATING HORMONE (HUMAN,MOUSE,R; (PHE13,TYR19)-MCH (; H-ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-PHE-ARG-PRO-CYS-TRP-GLN-TYR-OH; 黑色素聚集激素肽改造片段多肽[PHE13,TYR19]-MCH (HUMAN, MOUSE, RAT); H-ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-PHE-ARG-PRO-CYS-TRP-GLN-TYR; 化合物:(Phe13,Tyr1)-MCH (human, mouse, rat); 化合物：(Phe13,Tyr1)-MCH (human, mouse, rat); 人、小鼠、大鼠[苯丙氨酸13,酪氨酸19]促黑素聚集激素; (PHE13,TYR19)-MCH(人、小鼠、大鼠); ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-PHE-ARG-PRO-CYS-TRP-GLN-TYR (DISULFIDE BRIDGE: CYS7-CYS16)
• 英文别名: (Phe13,Tyr19)-Melanin-Concentrating Hormone (Human, Mouse, R; ASP-PHE-ASP-MET-LEU-G-CYS-MET-LEU-GLY-G-VAL-PHE-G-PRO-CYS-TRP-GLN-TYR; (Phe13,Tyr19)-MCH (huMan, Mouse, rat) (Phe13,Tyr19)-Melanin-Concentrating HorMone (MCH) (huMan, Mouse, rat); (Phe13,Tyr19)-Melanin-Concentrating Hormone (Human,Mouse,R; (PHE13,TYR19)-MELANIN-CONC; (PHE13,TYR19)-MCH (HUMAN, MOUSE, RAT); (Phe13,Tyr19)-MCH (huMan,Mouse,rat) (Phe13,Tyr19)-Melanin-Concentrating HorMone (MCH) (huMan,Mouse,rat); ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-PHE-ARG-PRO-CYS-TRP-GLN-TYR; H-ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-PHE-ARG-PRO-CYS-TRP-GLN-TYR-OH; (PHE13,TYR19)-MELANIN-CONCENTRATING HORMONE (HUMAN, MOUSE, RAT); L-Tyrosine, L-α-asptyl-L-phenylalanyl-L-α-asptyl-L-methionyl-L-leucyl-L-ginyl-L-cysteinyl-L-methionyl-L-leucylglycyl-L-ginyl-L-valyl-L-phenylalanyl-L-ginyl-L-prolyl-L-cysteinyl-L-tryptophyl-L-glutaminyl-, cyclic (7→16)-disulfide; PubChem ID; (Phe13,Tyr19)-MCH (human, mouse, rat) trifluoroacetate salt; H-ASP-PHE-ASP-MET-LEU-G-CYS-MET-LEU-GLY-G-VAL-PHE-G-PRO-CYS-TRP-GLN-TYR-OH; ASP-PHE-ASP-MET-LEU-G-CYS-MET-LEU-GLY-G-VAL-PHE-G-PRO-CYS-TRP-GLN-TYR (DISULFIDE BRIDGE: CYS7-CYS16); H-ASP-PHE-ASP-MET-LEU-G-CYS-MET-LEU-GLY-G-VAL-PHE-G-PRO-CYS-TRP-GLN-TYR-;H-ASP-PHE-ASP-MET-LEU-G-CYS-MET-LEU-GLY-G-VAL-PHE-G-PRO-CYS-TRP-GLN-TYR-OH;ASP-PHE-ASP-MET-LEU-G-CYS-MET-LEU-GLY-G-VAL-PHE-G-PRO-CYS-TRP-GLN-TYR;(PHE13,TYR19)-MCH (; H-ASP-PHE-ASP-MET-LEU-G-CYS-MET-LEU-GLY-G-VAL-PHE-G-PRO-CYS-TRP-GLN-TYR-;H-ASP-PHE-ASP-MET-LEU-G-CYS-MET-LEU-GLY-G-VAL-PHE-G-PRO-CYS-TRP-GLN-TYR-OH;ASP-PHE-ASP-MET-LEU-G-CYS-MET-LEU-GLY-G-VAL-PHE-G-PRO-CYS-TRP-GLN-TYR;(PHE13,TYR19)-MCH (HUMAN, MOUSE, RAT);(PHE13,TYR19)-MELANIN-CONCENTRATING HORMONE (HUMAN, MOUSE, R; (PHE13,TYR19)-MELANIN-CONCENTRATING HORMONE (MCH) (HUMAN, MOUSE, RAT); (PHE13,TYR19)-MELANIN-CONCENTRATING HORMONE (MCH) (HUMAN,MOUSE,RAT); (PHE13,TYR19)-MCH (HUMAN,MOUSE,RAT); H-Asp-Phe-Asp-Met-Leu-g-Cys-Met-Leu-Gly-g-Val-Phe-g-Pro-Cys-Trp-Gln-Tyr; (PHE13,TYR19)-MCH (; (PHE13,TYR19)-MELANIN-CONCENTRATING HORMONE (HUMAN,MOUSE,RAT); H-Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Phe-Arg-Pro-Cys-Trp-Gln-Tyr; Melanin-concentrating hormone(human),13-L-phenylalanine-19-L-tyrosine

物化性质

• 分子式: C₁₀₉H₁₆₀N₃₀O₂₆S₄
• 分子量: 2434.88000
• 精确质量: 2433.10000
• PSA: 1018.94000
• LogP: 7.13390
• 储存条件:

  保存方法： -15 °C

生物活性

• 描述: (Phe13,Tyr19)-MCH(人、小鼠、大鼠)是一种有效的SLC-1和S643b受体配体。(Phe13,Tyr19)-MCH(人、小鼠、大鼠)可用作SLC-1和S643b受体的激动剂[1]。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> MCHR1(GPR24)
  研究领域 >> 神经疾病
• 靶点:

  SLC-1/S643b[1]

• 参考文献:

  [1]. Rodriguez M, et al. Cloning and molecular characterization of the novel human melanin-concentrating hormone receptor MCH2. Mol Pharmacol. 2001 Oct;60(4):632-9.