16339-07-4

• 常用中文名：1-甲基-4-亚硝基哌嗪
• 常用英文名：Piperazine,1-methyl-4-nitroso
• CAS号：16339-07-4
• 分子式：C₅H₁₁N₃O
• 分子量：129.16000
• 发布时间：2018-07-14 16:18:02
• 更新时间：2026-07-21 14:12:45

名称

• 中文名: 1-甲基-4-亚硝基哌嗪
• 英文名: 1-methyl-4-nitrosopiperazine
• 中文别名: __PROTECTED__1-甲基-4-亚硝基哌嗪; N-亚硝基氯环嗪 杂质 A(N-亚硝基苯甲嗪 杂质 A、N-亚硝基苯甲嗪 相关化合物 A); 利福平相关杂质; 氯环利嗪杂质A; N-甲基-N'-亚硝哌嗪; N-亚硝基-N'-甲基哌嗪; N-甲基-N'-亚硝基哌嗪; 1-甲基-4-亚硝基哌嗪, MENP5; 左氧氟沙星杂质40
• 英文别名: N-Nitroso-N'-methylpiperazin; N-nitroso-N'-methylpiperazine; N-Nitroso-N'-methylpiperazine; Nsc523886; N-Methyl-N’-nitrosopiperazine in methanol; PIPERAZINE,1-METHYL-4-NITROSO; Methylnitrosopiperidine; NITROSO-N-METHYLPIPERAZINE; N-METHYLNITROSOPIPERAZINE; N-Nitrosomethylpiperazine; N-Nitroso Chlorcyclizine Impurity A; nitrosopiperazine; N-NITROSOMETHYLPIPERAZINE; 4-Methyl-1-nitrosopiperazine; NITROSOMETHYLPIPERAZINE; 1-methyl-4-nitrosopiperazine, MeNP5; N-Nitroso Chlorcyclizine Impurity A (N-Nitroso Cyclizine Impurity A, N-Nitroso Cyclizine Related Compound A); 1-Methyl-4-nitrosopiperazine Solution; 1-methyl-4-nitroso-piperazine; Levofloxacin Impurity 40; Olanzapine impurity 32; n-methyl-npz; N-Methylnitrosopiperazine; 1-NITROSO-4-METHYLPIPERAZINE; 1-Nitroso-4-methylpiperazine; N-Methyl-N’-nitrosopiperazine; N-Methyl-npz; Methylpiperazinenitrosamine

物化性质

• 密度: 1.2g/cm3
• 沸点: 236.9ºC at 760mmHg
• 分子式: C₅H₁₁N₃O
• 分子量: 129.16000
• 闪点: 97.1ºC
• 精确质量: 129.09000
• PSA: 35.91000
• 蒸汽压: 0.0463mmHg at 25°C
• 折射率: 1.561
• 储存条件: 室温

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TM1780000 CHEMICAL NAME : Piperazine, 1-methyl-4-nitroso- CAS REGISTRY NUMBER : 16339-07-4 BEILSTEIN REFERENCE NO. : 0117135 LAST UPDATED : 199612 DATA ITEMS CITED : 14 MOLECULAR FORMULA : C5-H11-N3-O MOLECULAR WEIGHT : 129.19 WISWESSER LINE NOTATION : T6N DNTJ ANO D1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 10 gm/kg/59W-C TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 20800 mg/kg/40W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 11440 mg/kg/22W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors TYPE OF TEST : Sex chromosome loss and nondisjunction TYPE OF TEST : Sex chromosome loss and nondisjunction MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 10 mmol/L REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 37,1044,1977

安全

• 海关编码: 2933599090

上下游产品

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海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%