Piperazine,1-methyl-4-nitroso-

Modify Date: 2025-08-24 17:54:15

Piperazine,1-methyl-4-nitroso- Structure
Piperazine,1-methyl-4-nitroso- structure
 Common Name Piperazine,1-methyl-4-nitroso-
CAS Number 16339-07-4 Molecular Weight 129.16000
Density 1.2g/cm3 Boiling Point 236.9ºC at 760mmHg
Molecular Formula C5H11N3O Melting Point N/A
MSDS N/A Flash Point 97.1ºC

 Names

Name 1-methyl-4-nitrosopiperazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2g/cm3
Boiling Point 236.9ºC at 760mmHg
Molecular Formula C5H11N3O
Molecular Weight 129.16000
Flash Point 97.1ºC
Exact Mass 129.09000
PSA 35.91000
Vapour Pressure 0.0463mmHg at 25°C
Index of Refraction 1.561

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TM1780000
CHEMICAL NAME :
Piperazine, 1-methyl-4-nitroso-
CAS REGISTRY NUMBER :
16339-07-4
BEILSTEIN REFERENCE NO. :
0117135
LAST UPDATED :
199612
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C5-H11-N3-O
MOLECULAR WEIGHT :
129.19
WISWESSER LINE NOTATION :
T6N DNTJ ANO D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 gm/kg/59W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20800 mg/kg/40W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
11440 mg/kg/22W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors
TYPE OF TEST :
Sex chromosome loss and nondisjunction
TYPE OF TEST :
Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
10 mmol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 37,1044,1977

 Safety Information

HS Code 2933599090

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

N-Nitrosomethylpiperazine
N-Nitroso-N'-methylpiperazine
1-Nitroso-4-methylpiperazine
N-Nitroso-N'-methylpiperazin
N-Methyl-npz
Methylpiperazinenitrosamine
N-Methylnitrosopiperazine
1-methyl-4-nitroso-piperazine
PIPERAZINE,1-METHYL-4-NITROSO
Methylnitrosopiperidine
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