136081-84-0

• 常用中文名：4-氧代-2-螺(哌啶-4-基)-苯并吡喃
• 常用英文名：SPIRO[CHROMENE-2,4'-PIPERIDIN]-4(3H)-ONE
• CAS号：136081-84-0
• 分子式：C₁₃H₁₅NO₂
• 分子量：217.26400
• 发布时间：2018-11-25 14:23:58
• 更新时间：2024-01-09 11:56:38

名称

• 中文名: 4-氧代-2-螺(哌啶-4-基)-苯并吡喃盐酸盐
• 英文名: Spiro[chromene-2,4'-piperidin]-4-(3H)-one
• 英文别名: spiro[3H-chromene-2,4'-piperidine]-4-one

物化性质

• 密度: 1.21g/cm3
• 沸点: 382.2ºC at 760 mmHg
• 分子式: C₁₃H₁₅NO₂
• 分子量: 217.26400
• 闪点: 185ºC
• 精确质量: 217.11000
• PSA: 38.33000
• LogP: 2.10280
• 蒸汽压: 4.79E-06mmHg at 25°C
• 折射率: 1.594
• 储存条件: 2-8℃，干燥，密封

安全

• 危害码 (欧洲): Xn
• 海关编码: 2934999090

合成路线

873779-32-9 ~10% 136081-84-0

文献：VERTEX PHARMACEUTICALS INCORPORATED; HADIDA-RUAH, Sara, Sabina; MILLER, Mark, Thomas; KALLEL, Edward, Adam; BEAR, Brian, Richard; ARUMUGAM, Vijayalaksmi; DENINNO, Michael, Paul; ZHOU, Jinglan; UY, Johnny; FRIEMAN, Bryan, A. Patent: WO2012/112743 A1, 2012 ; Location in patent: Page/Page column 70 ;

849928-22-9 ~96% 136081-84-0

文献：PFIZER PRODUCTS INC. Patent: WO2008/65508 A1, 2008 ; Location in patent: Page/Page column 21 ;

118-93-4 ~% 136081-84-0

文献：VERTEX PHARMACEUTICALS INCORPORATED; HADIDA-RUAH, Sara, Sabina; MILLER, Mark, Thomas; KALLEL, Edward, Adam; BEAR, Brian, Richard; ARUMUGAM, Vijayalaksmi; DENINNO, Michael, Paul; ZHOU, Jinglan; UY, Johnny; FRIEMAN, Bryan, A. Patent: WO2012/112743 A1, 2012 ;

19099-93-5 ~% 136081-84-0

文献：VERTEX PHARMACEUTICALS INCORPORATED; HADIDA-RUAH, Sara, Sabina; MILLER, Mark, Thomas; KALLEL, Edward, Adam; BEAR, Brian, Richard; ARUMUGAM, Vijayalaksmi; DENINNO, Michael, Paul; ZHOU, Jinglan; UY, Johnny; FRIEMAN, Bryan, A. Patent: WO2012/112743 A1, 2012 ;

203797-50-6 ~% 136081-84-0

文献：Yang, Lihu; Morriello, Greg; Prendergast, Kristine; Cheng, Kang; Jacks, Tom; Chan, Wanda W.-S.; Schleim, Klaus D.; Smith, Roy G.; Patchett, Arthur A. Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 1 p. 107 - 112

32161-06-1 ~% 136081-84-0

文献：Yang, Lihu; Morriello, Greg; Prendergast, Kristine; Cheng, Kang; Jacks, Tom; Chan, Wanda W.-S.; Schleim, Klaus D.; Smith, Roy G.; Patchett, Arthur A. Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 1 p. 107 - 112

上下游产品

上游产品  6
873779-32-9 849928-22-9 118-93-4 19099-93-5
203797-50-6 32161-06-1
下游产品  1
935534-37-5

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%