85955-59-5

• 常用中文名：(R)-赖诺普利钠盐
• 常用英文名：(2S)-1-[(2S)-6-amino-2-[[(1R)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
• CAS号：85955-59-5
• 分子式：C₂₁H₃₁N₃O₅
• 分子量：405.48800
• 发布时间：2017-10-17 23:29:49
• 更新时间：2026-08-05 16:07:08

名称

• 中文名: (R)-赖诺普利钠盐
• 英文名: (2S)-1-[(2S)-6-amino-2-[[(1R)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
• 中文别名: 赖诺普利杂质5(赖诺普利杂质E); LISINOPRIL 杂质E; (R)赖诺普利; 赖诺普利杂质E; (R,S,S)-赖诺普利; 利诺普利杂质E
• 英文别名: (S)-1-((S)-6-Amino-2-(((R)-1-cboxy-3-phenylpropyl)amino)hexanoyl)pyrrolidine-2-cboxylic acid; (2S)-1-[(2S)-6-amino-2-[[(1R)-1-cboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-cboxylic acid; Lisinopril Impurity EQ: What is Lisinopril Impurity E Q: What is the CAS Number of Lisinopril Impurity E Q: What is the storage condition of Lisinopril Impurity E Q: What e the applications of Lisinopril Impurity E; N2-((R)-1-carboxy-3-phenylpropyl)-L-lysyl-L-proline; Lisinopril Impurity 5(Lisinopril Impurity E); Lisinopril dihydrate impurity E; (R)-1-[N2-(1-Cboxy-3-phenylpropyl)-L-lysyl]L-proline; Lisinopril Impurity; (2S)-1-[(2S)-6-amino-2-[[(2R)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid; L-Proline, N2-[(1R)-1-cboxy-3-phenylpropyl]-L-lysyl; Lisinopril-Imp-E; N2-[(1R)-1-Cboxy-3-phenylpropyl)-L-lysyl]L-proline; (R)-Lisinopril Sodium Salt; (R) Lisinopril; Lisinopril impurity 4/Lisinopril Impurity E/Lisinopril imer; Lisinopril (R,S,S)-Isomer

物化性质

• 密度: 1.252g/cm3
• 沸点: 666.441ºC at 760 mmHg
• 分子式: C₂₁H₃₁N₃O₅
• 分子量: 405.48800
• 闪点: 356.851ºC
• 精确质量: 405.22600
• PSA: 132.96000
• LogP: 2.26430
• 折射率: 1.578

合成路线

710-11-2 4583-24-8 ~% 76547-98-3 85955-59-5

文献：Wu; Douglas; Ondeyka; Payne; Ikeler; Joshua; Patchett Journal of pharmaceutical sciences, 1985 , vol. 74, # 3 p. 352 - 354

77726-95-5 ~0% 76547-98-3 85955-59-5

文献：Boisivon, Frédéric; Debas, Jean; Richet, Gérard Patent: US2011/77412 A1, 2011 ; Location in patent: Page/Page column 2 ;

16652-71-4 ~% 85955-59-5

文献：Wu; Douglas; Ondeyka; Payne; Ikeler; Joshua; Patchett Journal of pharmaceutical sciences, 1985 , vol. 74, # 3 p. 352 - 354

90826-23-6 ~% 85955-59-5

文献：Wu; Douglas; Ondeyka; Payne; Ikeler; Joshua; Patchett Journal of pharmaceutical sciences, 1985 , vol. 74, # 3 p. 352 - 354

103300-91-0 ~0% 76547-98-3 85955-59-5

文献：Blacklock; Shuman; Butcher; Shearin Jr.; Budavari; Grenda Journal of Organic Chemistry, 1988 , vol. 53, # 4 p. 836 - 844

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