103300-91-0

• 常用中文名：N2-[1-(S)-乙氧羰基-3-苯丙基]-N6-三氟乙酰基-L-赖氨酸-L-脯氨酸
• 常用英文名：Lisinopril ester
• CAS号：103300-91-0
• 分子式：C₂₅H₃₄F₃N₃O₆
• 分子量：529.549
• 相关类别： 生物化工 氨基酸及其衍生物 赖氨酸类衍生物
• 发布时间：2018-12-04 20:17:30
• 更新时间：2026-08-08 13:18:21

名称

• 中文名: N2-[1-(S)-乙氧羰基-3-苯丙基]-N6-三氟乙酰基-L-赖氨酸-L-脯氨酸
• 英文名: N2-1[(1S)-Ethoxycarbonyl-3-phenylpropyl]-N6-trifluoroacetyl-L-lysyl-L-proline
• 中文别名: N2-((S)-1-乙氧基-1-氧代-4-苯基丁-2-基)-N6-(2,2,2-三氟乙烷酰基)-L-赖氨酸-L-脯氨酸; 赖诺普利杂质28; N2-[1-(S)-乙氧羰基-3-苯丙基]-N6-三氟乙酰基-L-赖氨; N2-[1-(S)-乙氧羰基-3-苯丙基]-N6-三氟乙酰基-L-赖氨/A>; N2-1-(S)-乙氧羰基-3-苯丙基-N6-三氟乙酰基-L-赖氨酸-L-脯氨酸
• 英文别名: (S)-1-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-6-(2,2,2-trifluoroacetamido)hexanoyl); Lisinopril Impurity 28; N-[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]-N-(trifluoroacetyl)-L-lysyl-L-proline; N2-[(S)-1-Ethoxycbonyl-3-phenylpropyl]-N6-trifluoroacetyl-L-lysyl-L-proline; N-[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]-N-(trifluoroacetyl)-L-lysyl-L-proline; N2-[(1S)-1-(Ethoxycbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl-L-proline; N2-1[(1S)-Ethoxycbonyl-3-phenylpropyl]-N6-trifluoroacetyl; (S)-1-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-6-(2,2,2-trifluoroacetamido)hexano; Lisinopri Impurity; lisinopril ester; N2-(1-(S)-ethoxycbqonyl-3-phenylpropyl)-N6-trifluoroacetyl-L-lysine-L-proline; N2-1[(1S)-Ethoxycbonyl-3-phenylpropyl]-N6-trifluoroacetyl-L-lysyl-L-proline //BP; LISINOPRIL (ETHYL) ESTER; N2-[(S)-1-(Ethoxycbonyl)-3-phenylpropyl]-N6-(trifluoroacetyl)-L-Lys-L-Pro-OH; N2-1[(1S)-Ethoxycbonyl-3-phenylpropyl]-N6-trifluoroacetyl-L-lysyl-L-proline; N2-[(S)-3-Phenyl-1-(ethoxycbonyl)propyl]-N6-(trifluoroacetyl)-L-Lys-L-Pro-OH; 1-[N2-[(1S)-Ethoxycbonyl-3-phenylpropyl]-N6-trifluoroacetyl]-L-lysyl-L-proline; L-Proline,N2-[(1S)-1-(ethoxycbonyl)-3-phenylpropyl]-N6-(2,2,2-trifluoroacetyl)-L-lysyl; Lisinopri Impurity 28; L-PROLINE, N2-[(1S)-1-(ETHOXYCBONYL)-3-PHENYLPROPYL]-N6-(TRIFLUOROACETYL)-L-LYSYL- SOLUTION; 1-N-(1-Ethoxycbonyl)-3-phenylpropyl)-N 6-triflouracetyl-L lysyl-L-prolin; (S)-1-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-6-(2,2,2-trifluoroacetaMido)hexanoyl)pyrrolidine-2-cboxylic acid; Lisinopril(TFA)-ethyl ester; N2-[(S)-1-Ethoxycbonyl-3-phenylpropyl]-N6-triflu; N2-[(S)-ETHOXYCBONYL-3-PHENYLPROPYL]-N6-TRIFLUOROACETYL-L-LYSYL-L-PROLINE; LISINOPRIL ESTER; Lisinopril intermediate; 1-[N2-[(S)-1-(Ethoxycbonyl)-3-phenylpropyl]-N6-(trifluoroacetyl)-L-lysyl]-L-proline; 2-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-6-[(2,2,2-trifluoro-1-oxoethyl)amino]hexanoic acid

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 714.8±60.0 °C at 760 mmHg
• 分子式: C₂₅H₃₄F₃N₃O₆
• 分子量: 529.549
• 闪点: 386.1±32.9 °C
• 精确质量: 529.239990
• PSA: 125.04000
• LogP: 2.89
• 蒸汽压: 0.0±2.4 mmHg at 25°C
• 折射率: 1.519

合成路线

64920-29-2 103300-89-6 ~% 112246-14-7 103300-91-0

文献：Journal of Organic Chemistry, , vol. 53, # 4 p. 836 - 844

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