66922-67-6

• 常用中文名：ETHYLPHENACETIN
• 常用英文名：ETHYLPHENACETIN
• CAS号：66922-67-6
• 分子式：C₁₂H₁₇NO₂
• 分子量：207.26900
• 发布时间：2017-04-02 18:22:53
• 更新时间：2024-01-09 19:09:02

名称

• 英文名: N-(4-ethoxyphenyl)-N-ethylacetamide
• 英文别名: Ethylphenacetin; p-ACETOPHENETIDIDE,N-ETHYL; N-Aethyl-phenacetin

物化性质

• 密度: 1.046g/cm3
• 沸点: 324.3ºC at 760 mmHg
• 分子式: C₁₂H₁₇NO₂
• 分子量: 207.26900
• 闪点: 149.9ºC
• 精确质量: 207.12600
• PSA: 29.54000
• LogP: 2.45810
• 折射率: 1.529

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AM4400000 CHEMICAL NAME : p-Acetophenetidide, N-ethyl- CAS REGISTRY NUMBER : 66922-67-6 BEILSTEIN REFERENCE NO. : 3274909 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C12-H17-N-O2 MOLECULAR WEIGHT : 207.30 WISWESSER LINE NOTATION : 2OR DN2&V1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 2500 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - acute pulmonary edema Blood - other changes REFERENCE : AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 33,216,1894 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 2700 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - ataxia Cardiac - other changes REFERENCE : AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 33,216,1894 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Amphibian - frog DOSE/DURATION : 3 gm/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Cardiac - pulse rate Cardiac - other changes REFERENCE : AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 33,216,1894

合成路线

65570-13-0 108-24-7 ~% 66922-67-6

文献：Park et al. Journal of the American Chemical Society, 1951 , vol. 73, p. 5898

64-67-5 62-44-2 ~% 66922-67-6

文献：Brehme, R.; Thelen, P. Journal fuer Praktische Chemie (Leipzig), 1981 , vol. 323, # 2 p. 299 - 302

103-90-2 ~% 66922-67-6

文献：Hinsberg Justus Liebigs Annalen der Chemie, 1899 , vol. 305, p. 287

156-43-4 ~% 66922-67-6

文献：Hinsberg Justus Liebigs Annalen der Chemie, 1899 , vol. 305, p. 287

62-44-2 75-03-6 ~% 66922-67-6

文献：Hinsberg Justus Liebigs Annalen der Chemie, 1899 , vol. 305, p. 287 Full Text Show Details Bayer and Co. Patent: DE54990 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 2, p. 528

74-96-4 103-90-2 ~% 66922-67-6

文献：Bayer and Co. Patent: DE57338 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 908

108-24-7 ~% 66922-67-6

文献：Bayer and Co. Patent: DE57338 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 908

上下游产品

上游产品  7
108-24-7 64-67-5 62-44-2 103-90-2
156-43-4 75-03-6 74-96-4
下游产品  1
91457-25-9