ETHYLPHENACETIN

Modify Date: 2025-11-25 11:58:55

ETHYLPHENACETIN Structure
ETHYLPHENACETIN structure
Common Name ETHYLPHENACETIN
CAS Number 66922-67-6 Molecular Weight 207.26900
Density 1.046g/cm3 Boiling Point 324.3ºC at 760 mmHg
Molecular Formula C12H17NO2 Melting Point N/A
MSDS N/A Flash Point 149.9ºC

 Names

Name N-(4-ethoxyphenyl)-N-ethylacetamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.046g/cm3
Boiling Point 324.3ºC at 760 mmHg
Molecular Formula C12H17NO2
Molecular Weight 207.26900
Flash Point 149.9ºC
Exact Mass 207.12600
PSA 29.54000
LogP 2.45810
Index of Refraction 1.529
InChIKey IWXURAOZPFLNQM-UHFFFAOYSA-N
SMILES CCOc1ccc(N(CC)C(C)=O)cc1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AM4400000
CHEMICAL NAME :
p-Acetophenetidide, N-ethyl-
CAS REGISTRY NUMBER :
66922-67-6
BEILSTEIN REFERENCE NO. :
3274909
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C12-H17-N-O2
MOLECULAR WEIGHT :
207.30
WISWESSER LINE NOTATION :
2OR DN2&V1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - acute pulmonary edema Blood - other changes
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 33,216,1894
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
2700 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Cardiac - other changes
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 33,216,1894
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Cardiac - pulse rate Cardiac - other changes
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 33,216,1894

 Synthetic Route

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ETHYLPHENACETIN Structure

ETHYLPHENACETIN

CAS#:66922-67-6

Literature: Park et al. Journal of the American Chemical Society, 1951 , vol. 73, p. 5898

~%

ETHYLPHENACETIN Structure

ETHYLPHENACETIN

CAS#:66922-67-6

Literature: Brehme, R.; Thelen, P. Journal fuer Praktische Chemie (Leipzig), 1981 , vol. 323, # 2 p. 299 - 302

~%

ETHYLPHENACETIN Structure

ETHYLPHENACETIN

CAS#:66922-67-6

Literature: Hinsberg Justus Liebigs Annalen der Chemie, 1899 , vol. 305, p. 287

~%

ETHYLPHENACETIN Structure

ETHYLPHENACETIN

CAS#:66922-67-6

Literature: Hinsberg Justus Liebigs Annalen der Chemie, 1899 , vol. 305, p. 287

~%

ETHYLPHENACETIN Structure

ETHYLPHENACETIN

CAS#:66922-67-6

Literature: Hinsberg Justus Liebigs Annalen der Chemie, 1899 , vol. 305, p. 287 Full Text Show Details Bayer and Co. Patent: DE54990 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 2, p. 528

~%

ETHYLPHENACETIN Structure

ETHYLPHENACETIN

CAS#:66922-67-6

Literature: Bayer and Co. Patent: DE57338 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 908

~%

ETHYLPHENACETIN Structure

ETHYLPHENACETIN

CAS#:66922-67-6

Literature: Bayer and Co. Patent: DE57338 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 908

 Synonyms

Ethylphenacetin
p-ACETOPHENETIDIDE,N-ETHYL
N-Aethyl-phenacetin
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