374794-90-8

• 常用中文名：4-(3-乙氧基-3-氧代-1-丙炔-1-基)-4-羟基-1-哌啶羧酸 1,1-二甲基乙酯
• 常用英文名：1-Piperidinecarboxylic acid, 4-(3-ethoxy-3-oxo-1-propyn-1-yl)-4-hydroxy-, 1,1-dimethylethyl ester
• CAS号：374794-90-8
• 分子式：C₁₅H₂₃NO₅
• 分子量：297.34700
• 发布时间：2018-07-26 19:42:33
• 更新时间：2026-07-04 19:38:56

名称

• 中文名: 4-(3-乙氧基-3-氧代-1-丙炔-1-基)-4-羟基-1-哌啶羧酸 1,1-二甲基乙酯
• 英文名: 2-Methyl-2-propanyl 4-(3-ethoxy-3-oxo-1-propyn-1-yl)-4-hydroxy-1- piperidinecarboxylate
• 中文别名: 3-(1-BOC-4-羟基-4-哌啶基)丙炔酸乙酯; 4-(3-乙氧基-3-氧代丙-1-炔-1-基)-4-羟基哌啶-1-甲酸叔丁酯; 4-(3-乙氧基-3-氧代丙-1-炔-1-基)-4-羟基哌啶-1-羧酸叔丁酯
• 英文别名: 1-Boc-4-(2-Cyano-1-hydroxyethyl)piperidine; 4-(3-Ethoxy-3-oxo-1-propyn-1-yl)-4-hydroxy-1-piperidinecboxylic Acid 1,1-dimethylethyl Ester; tert-Butyl 4-(3-ethoxy-3-oxoprop-1-yn-1-yl)-4-hydroxypiperidine-1-cboxylate; Ethyl 3-(1-Boc-4-hydroxy-4-piperidyl)propiolate; 2-methyl-2-propanyl 4-(3-ethoxy-3-oxo-1-propyn-1-yl)-4-hydroxy-1- Piperidinecboxylate; 1-Piperidinecboxylic acid, 4-(3-ethoxy-3-oxo-1-propyn-1-yl)-4-hydroxy-, 1,1-diMethylethyl ester; 1,1-dimethylethyl 4-(2-cyano-1-hydroxyethyl)-1-piperidinecarboxylate; 1,1-dimethylethyl 4-(3-ethoxy-3-oxo-1-propynyl)-4-hydroxy-1-piperidinecarboxylate

物化性质

• 密度: 1.182g/cm3
• 沸点: 426.804ºC at 760 mmHg
• 分子式: C₁₅H₂₃NO₅
• 分子量: 297.34700
• 闪点: 211.924ºC
• 精确质量: 297.15800
• PSA: 76.07000
• LogP: 1.25280
• 折射率: 1.521

合成路线

79099-07-3 623-47-2 ~% 374794-90-8

文献：Cooper, Laura C.; Carlson, Emma J.; Castro, Jose L.; Chicchi, Gary G.; Dinnell, Kevin; Di Salvo, Jerry; Elliott, Jason M.; Hollingworth, Gregory J.; Kurtz, Marc M.; Ridgill, Mark P.; Rycroft, Wayne; Tsao, Kwei-Lan; Swain, Christopher J. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 13 p. 1759 - 1762

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