374794-88-4

• 常用中文名：4-羟基-4-(3-羟基丙基)-1-哌啶羧酸 1,1-二甲基乙酯
• 常用英文名：1-Piperidinecarboxylic acid, 4-hydroxy-4-(3-hydroxypropyl)-, 1,1-dimethylethyl ester
• CAS号：374794-88-4
• 分子式：C₁₃H₂₅NO₄
• 分子量：259.34200
• 发布时间：2018-12-08 16:58:26
• 更新时间：2024-01-09 09:10:52

名称

• 中文名: 4-羟基-4-(3-羟基丙基)-1-哌啶羧酸 1,1-二甲基乙酯
• 英文名: 2-Methyl-2-propanyl 4-hydroxy-4-(3-hydroxypropyl)-1-piperidinecar boxylate

物化性质

• 密度: 1.119g/cm3
• 沸点: 378.949ºC at 760 mmHg
• 分子式: C₁₃H₂₅NO₄
• 分子量: 259.34200
• 闪点: 182.982ºC
• 精确质量: 259.17800
• PSA: 70.00000
• LogP: 1.45880
• 折射率: 1.502

合成路线

374794-87-3 ~56% 374794-88-4

文献：MERCK SHARP and DOHME LIMITED Patent: WO2004/78750 A1, 2004 ; Location in patent: Page 77-78 ; WO 2004/078750 A1

1192122-44-3 ~% 374794-88-4

文献：Astellas Pharma Inc. Patent: WO2009/131246 A1, 2009 ; Location in patent: Page/Page column 87 ;

301226-27-7 ~% 374794-88-4

文献：Cooper, Laura C.; Carlson, Emma J.; Castro, Jose L.; Chicchi, Gary G.; Dinnell, Kevin; Di Salvo, Jerry; Elliott, Jason M.; Hollingworth, Gregory J.; Kurtz, Marc M.; Ridgill, Mark P.; Rycroft, Wayne; Tsao, Kwei-Lan; Swain, Christopher J. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 13 p. 1759 - 1762

79099-07-3 ~% 374794-88-4

文献：Cooper, Laura C.; Carlson, Emma J.; Castro, Jose L.; Chicchi, Gary G.; Dinnell, Kevin; Di Salvo, Jerry; Elliott, Jason M.; Hollingworth, Gregory J.; Kurtz, Marc M.; Ridgill, Mark P.; Rycroft, Wayne; Tsao, Kwei-Lan; Swain, Christopher J. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 13 p. 1759 - 1762

374794-90-8 ~% 374794-88-4

文献：Cooper, Laura C.; Carlson, Emma J.; Castro, Jose L.; Chicchi, Gary G.; Dinnell, Kevin; Di Salvo, Jerry; Elliott, Jason M.; Hollingworth, Gregory J.; Kurtz, Marc M.; Ridgill, Mark P.; Rycroft, Wayne; Tsao, Kwei-Lan; Swain, Christopher J. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 13 p. 1759 - 1762

374794-91-9 ~% 374794-88-4

文献：Cooper, Laura C.; Carlson, Emma J.; Castro, Jose L.; Chicchi, Gary G.; Dinnell, Kevin; Di Salvo, Jerry; Elliott, Jason M.; Hollingworth, Gregory J.; Kurtz, Marc M.; Ridgill, Mark P.; Rycroft, Wayne; Tsao, Kwei-Lan; Swain, Christopher J. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 13 p. 1759 - 1762

上下游产品

上游产品  5
374794-87-3 301226-27-7 79099-07-3 374794-90-8
374794-91-9
下游产品  1
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