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| 中文名 | 鸟苷-5'-三磷酸二钠盐 |
|---|---|
| 英文名 | Guanosine 5‘-triphosphate, disodium salt hydrate |
| 中文别名 |
三磷酸鸟苷二钠盐
鸟苷-5'-三磷酸二钠 5-鸟苷三磷酸二钠盐 |
| 英文别名 |
Disodium 5'-O-({[(phosphonooxy)phosphinato]oxy}phosphinato)guanosine
Guanosine, 5'-(tetrahydrogen triphosphate), sodium salt (1:2) Guanosine-5'-triphosphoric aicd disodium salt MFCD00083629 EINECS 252-847-2 |
| 描述 | Guanosine-5'-triphosphate disodium salt (5'-GTP trisodium salt) 是 G 蛋白信号转导活化剂,也是 DNA 和 RNA 酶生物合成中单核苷单元的富能量前体。 |
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| 相关类别 | |
| 参考文献 |
| 沸点 | 1028.3ºC at 760mmHg |
|---|---|
| 熔点 | 180°C |
| 分子式 | C10H14N5Na2O14P3 |
| 分子量 | 567.144 |
| 闪点 | 575.7ºC |
| 精确质量 | 566.954529 |
| PSA | 334.19000 |
| 外观性状 | 无气味的白色固体 |
| 储存条件 | 密封、在 -20ºC下保存 |
| 稳定性 | 如果遵照规格使用和储存则不会分解，未有已知危险反应 |
| 计算化学 | 1、 疏水参数计算参考值（XlogP）：-6.8 2、 氢键供体数量：4 3、 氢键受体数量：17 4、 可旋转化学键数量：7 5、 互变异构体数量：6 6、 拓扑分子极性表面积（TPSA）：306 7、 重原子数量：32 8、 表面电荷：-4 9、 复杂度：899 10、同位素原子数量：0 11、确定原子立构中心数量：4 12、不确定原子立构中心数量：0 13、确定化学键立构中心数量：0 14、不确定化学键立构中心数量：0 15、共价键单元数量：1 |
| 更多 | 1. 性状：固体 2. 密度（g/mL,15ºC）：未确定 3. 相对蒸汽密度（g/mL,空气=1）： 未确定 4. 熔点（ºC）：180 5. 沸点（ºC）：未确定 6. 沸点（ºC，0.5mmHg）：未确定 7. 折射率：未确定 8. 闪点（°F）：未确定 9. 比旋光度（ºC）：未确定 10. 自燃点或引燃温度（ºC）： 未确定 11. 蒸气压（kPa,25ºC）：未确定 12. 饱和蒸气压（kPa,60ºC）：未确定 13. 燃烧热（KJ/mol）：未确定 14. 临界温度（ºC）：未确定 15. 临界压力（KPa）：未确定 16. 油水（辛醇/水）分配系数的对数值：未确定 17. 爆炸上限（%,V/V）：未确定 18. 爆炸下限（%,V/V）：未确定 19. 溶解性：未确定 |
Synonym:GTP disodium sal Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Moisture sensitive. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a tightly closed container. Keep under an argon blanket. Keep refrigerated. (Store below 4C/39F.) Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Exposure Limits CAS# 56001-37-7: Personal Protective Equipment Eyes: Wear chemical splash goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear a chemical apron. Respirators: A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: white Odor: Odorless pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 180 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: soluble in water Specific Gravity/Density: Molecular Formula: C10H14N5O14P3Na2.2H2O Molecular Weight: 567.14 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: High temperatures, incompatible materials, heating to decomposition, exposure to moist air or water. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, oxides of phosphorus, carbon dioxide. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 56001-37-7 unlisted. LD50/LC50: Not available. Carcinogenicity: Guanosine 5'-triphosphate, disodium salt dihydrate - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Ecotoxicity: Water danger/protection: WGK 1 Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 56001-37-7: 1 Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 56001-37-7 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 56001-37-7 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
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生态学数据: 对水是稍微有危害的不要让未稀释或大量的产品接触地下水、水道或者污水系统，若无政府许可，勿将材料排入周围环境
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| 危害码 (欧洲) | Xi |
|---|---|
| 风险声明 (欧洲) | R36/37/38 |
| 安全声明 (欧洲) | 26-27-36/37/39 |
| WGK德国 | 3 |