79759-47-0

• 常用中文名：6-chloro-3-phenyl-1H-benzimidazol-2-one
• 常用英文名：6-chloro-3-phenyl-1H-benzimidazol-2-one
• CAS号：79759-47-0
• 分子式：C₁₃H₉ClN₂O
• 分子量：244.67600
• 发布时间：2016-12-17 00:16:16
• 更新时间：2024-01-10 17:56:39

名称

• 英文名: 6-chloro-3-phenyl-1H-benzimidazol-2-one
• 英文别名: 5-chloro-1-phenyl-1,3-dihydro-2H-benzimidazol-2-one; 5-Chloro-1-phenyl-1,3-dihydro-benzoimidazol-2-one; 1,3-Dihydro-5-chloro-1-phenyl-2H-benzimidazol-2-one; 2H-Benzimidazol-2-one,1,3-dihydro-5-chloro-1-phenyl

物化性质

• 密度: 1.372g/cm3
• 分子式: C₁₃H₉ClN₂O
• 分子量: 244.67600
• 精确质量: 244.04000
• PSA: 38.05000
• LogP: 3.38450
• 折射率: 1.657

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DE2275939 CHEMICAL NAME : 2H-Benzimidazol-2-one, 1,3-dihydro-5-chloro-1-phenyl- CAS REGISTRY NUMBER : 79759-47-0 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C13-H9-Cl-N2-O MOLECULAR WEIGHT : 244.69 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 16,321,1981

合成路线

32315-10-9 42837-74-1 ~94% 79759-47-0

文献：Taliani, Sabrina; Pugliesi, Isabella; Barresi, Elisabetta; Simorini, Francesca; Salerno, Silvia; La Motta, Concettina; Marini, Anna Maria; Cosimelli, Barbara; Cosconati, Sandro; Di Maro, Salvatore; Marinelli, Luciana; Daniele, Simona; Trincavelli, Maria Letizia; Greco, Giovanni; Novellino, Ettore; Martini, Claudia; Da Settimo, Federico Journal of Medicinal Chemistry, 2012 , vol. 55, # 4 p. 1490 - 1499

79759-23-2 ~10% 79759-47-0

文献：Bianchi; Butti; Rossi; et al. European Journal of Medicinal Chemistry, 1981 , vol. 16, # 4 p. 321 - 326

42837-74-1 ~% 79759-47-0

文献：Bianchi; Butti; Rossi; et al. European Journal of Medicinal Chemistry, 1981 , vol. 16, # 4 p. 321 - 326