CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
VA4146600
-
CHEMICAL NAME :
-
4(3H)-Quinazolinone, 2-methyl-3-(2,5-xylyl)-
-
CAS REGISTRY NUMBER :
-
10367-31-4
-
LAST UPDATED :
-
199612
-
DATA ITEMS CITED :
-
2
-
MOLECULAR FORMULA :
-
C17-H16-N2-O
-
MOLECULAR WEIGHT :
-
264.35
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
>1200 mg/kg
-
TOXIC EFFECTS :
-
Behavioral - somnolence (general depressed activity)
-
REFERENCE :
-
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,129,1967
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
710 mg/kg
-
TOXIC EFFECTS :
-
Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
-
REFERENCE :
-
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 17,616,1962
|
