CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
LL8400000
-
CHEMICAL NAME :
-
Fluorene, 2-nitroso-
-
CAS REGISTRY NUMBER :
-
2508-20-5
-
LAST UPDATED :
-
199710
-
DATA ITEMS CITED :
-
11
-
MOLECULAR FORMULA :
-
C13-H9-N-O
-
MOLECULAR WEIGHT :
-
195.23
-
WISWESSER LINE NOTATION :
-
L B656 HHJ ENO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
160 mg/kg/4W-I
-
TOXIC EFFECTS :
-
Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
200 mg/kg/8W-I
-
TOXIC EFFECTS :
-
Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
MUTATION DATA
-
TYPE OF TEST :
-
DNA damage
-
TEST SYSTEM :
-
Bacteria - Bacillus subtilis
-
DOSE/DURATION :
-
1 mmol/L
-
REFERENCE :
-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 42,175,1977
|