162702-04-7

• 常用中文名：N-(4-氰基-3-甲基-1,2-噻唑-5-基)-3-甲基丁酰胺
• 常用英文名：N-(4-cyano-3-methyl-1,2-thiazol-5-yl)-3-methylbutanamide
• CAS号：162702-04-7
• 分子式：C₁₀H₁₃N₃OS
• 分子量：223.29500
• 发布时间：2018-10-16 23:07:31
• 更新时间：2025-08-28 00:30:43

名称

• 中文名: N-(4-氰基-3-甲基-1,2-噻唑-5-基)-3-甲基丁酰胺
• 英文名: N-(4-cyano-3-methyl-1,2-thiazol-5-yl)-3-methylbutanamide
• 英文别名: N-(4-cyano-3-methyl-isothiazol-5-yl)-3-methyl-butyramide; Butanamide,N-(4-cyano-3-methyl-5-isothiazolyl)-3-methyl

物化性质

• 分子式: C₁₀H₁₃N₃OS
• 分子量: 223.29500
• 精确质量: 223.07800
• PSA: 97.51000
• LogP: 2.95728

合成路线

108-12-3 41808-35-9 ~87% 162702-04-7

文献：AstraZeneca AB Patent: US2006/41128 A1, 2006 ; Location in patent: Page/Page column 12 ;

758721-53-8 ~% 162702-04-7

文献：Theoclitou, Maria-Elena; Aquila, Brian; Block, Michael H.; Brassil, Patrick J.; Castriotta, Lillian; Code, Erin; Collins, Michael P.; Davies, Audrey M.; Deegan, Tracy; Ezhuthachan, Jayachandran; Filla, Sandra; Freed, Ellen; Hu, Haiqing; Huszar, Dennis; Jayaraman, Muthusamy; Lawson, Deborah; Lewis, Paula M; Nadella, Murali V. P.; Oza, Vibha; Padmanilayam, Maniyan; Pontz, Timothy; Ronco, Lucienne; Russell, Daniel; Whitston, David; Zheng, Xiaolan Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6734 - 6750

116595-42-7 ~% 162702-04-7

文献：Theoclitou, Maria-Elena; Aquila, Brian; Block, Michael H.; Brassil, Patrick J.; Castriotta, Lillian; Code, Erin; Collins, Michael P.; Davies, Audrey M.; Deegan, Tracy; Ezhuthachan, Jayachandran; Filla, Sandra; Freed, Ellen; Hu, Haiqing; Huszar, Dennis; Jayaraman, Muthusamy; Lawson, Deborah; Lewis, Paula M; Nadella, Murali V. P.; Oza, Vibha; Padmanilayam, Maniyan; Pontz, Timothy; Ronco, Lucienne; Russell, Daniel; Whitston, David; Zheng, Xiaolan Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6734 - 6750

5417-82-3 ~% 162702-04-7

文献：Theoclitou, Maria-Elena; Aquila, Brian; Block, Michael H.; Brassil, Patrick J.; Castriotta, Lillian; Code, Erin; Collins, Michael P.; Davies, Audrey M.; Deegan, Tracy; Ezhuthachan, Jayachandran; Filla, Sandra; Freed, Ellen; Hu, Haiqing; Huszar, Dennis; Jayaraman, Muthusamy; Lawson, Deborah; Lewis, Paula M; Nadella, Murali V. P.; Oza, Vibha; Padmanilayam, Maniyan; Pontz, Timothy; Ronco, Lucienne; Russell, Daniel; Whitston, David; Zheng, Xiaolan Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6734 - 6750