10595-95-6

• 常用中文名：N-亚硝基甲基乙基胺
• 常用英文名：N-Methyl-N-nitrosoethanamine
• CAS号：10595-95-6
• 分子式：C₃H₈N₂O
• 分子量：88.108
• 发布时间：2018-05-18 08:00:00
• 更新时间：2026-07-01 20:46:21

• 1. 用于生化研究。

名称

• 中文名: N-亚硝基甲乙胺
• 英文名: N-Nitrosoethylmethylamine
• 中文别名: 甲醇中N-亚硝基乙基甲基胺; N-亚硝基甲基乙基胺(标准品); 二氯甲烷中N-亚硝基乙基甲基胺; N-亚硝基乙基甲基胺; 乙基甲基亚硝酰胺; 甲基乙基亚硝胺; 亚硝基甲基乙基胺; N-乙基-N-甲基亚硝酰胺; 乙基甲基亚硝胺; N-乙基-N-甲基硝基US 酰胺; N-亚硝基乙基甲基胺 (NEMA)溶液, 100PPM; N-亚硝基二异丙基胺-D7; N-亚硝基甲基乙基胺（标准品）; N-亚硝基乙基甲胺; N-硝基甲基乙胺; N-亚硝基甲基乙基胺(NEMA); 甲醇中N-亚硝基乙基甲基胺 (NEMA)溶液,100ΜG/ML; N-亚硝基甲基乙胺; N-NITROSOETHYLMETHYLAMINE N-亚硝基甲乙胺; N-亚硝基-N-甲基乙胺; N-亚硝基甲乙胺(标准品); 甲醇中N-亚硝基甲乙胺标准溶液; N-亚硝基乙基甲基胺 (NEMA)
• 英文别名: n-nitroso-n-methylethylamine; Methylaethylnitrosamin; N-Nitrosomethylethylamine@100 μg/mL in Dichloromethane; N-nitroso methylamine; N-Nitrosoniummethylethylamine; Ethanamine, N-methyl-N-nitroso; N-Nitroso; Nitrosoethylmethylamine; N-ethyl-N-methylnitrous amide; N-Nitroso-N-methyl ethylamine; Ethylamine, N-methyl-N-nitroso; Ethylmethylnitrosamine; N-Methyl-N-nitrosoethylamine; N-Methyl-N-nitroso-ethamine; N-Nitrosomethylethylamine 100mg [10-6]; Methylethylnitrosoamine; Nmea; N-Methyl-N-ethylnitrosamine; N-Nitrosoethylmethylamine 100 μg/ml Methanol; N-Nitroso-methyl-ethylamine 1000 μg/mL in Methanol; N-NITROSO-METHYL-ETHYLAMINE; N-Nitroso-methyl ethylamine Solution in Methanol, 100μg/mL; Nitrosomethylethylamine; N-Nitrosodiisopropyl Amine-d7; n-nitroso-methyl-ethylamine; N,N-Methylethylnitrosamine; 1-Ethyl-1-methyl-2-oxohydrazine; N-Nethyl-N-nitrosoethylaMine; N-Nitrosomethylethylamine in dichloromethane; N-(nitrosomethyl)ethanamine; N-Nitroso-N-methyl ethylamine@1000 μg/mL in Methanol; n-methyl-n-nitroso-ethylamin; N-Nitrosoethylmethylamine (Mixture of Isomers); n-methyl-n-nitroso-ethanamin; METHYL ETHYL NITROSAMINE

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 154.4±9.0 °C at 760 mmHg
• 分子式: C₃H₈N₂O
• 分子量: 88.108
• 闪点: 47.2±18.7 °C
• 精确质量: 88.063660
• PSA: 32.67000
• LogP: -0.11
• 蒸汽压: 4.1±0.3 mmHg at 25°C
• 折射率: 1.436
• 储存条件: 室温
• 稳定性:

  1. 存在于烟气中。

  2. 有致癌的可能性。

• 分子结构:

  1、 摩尔折射率：23.85

  2、 摩尔体积（cm³/mol）：91.2

  3、 等张比容（90.2K）：214.6

  4、 表面张力（dyne/cm）：30.6

  5、 极化率（10-24cm3）：9.45

• 更多:

  1. 沸点（ºC）：67（5332pa）

  2. 性状：黄色液体。

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KR9200000 CHEMICAL NAME : Ethylamine, N-methyl-N-nitroso- CAS REGISTRY NUMBER : 10595-95-6 BEILSTEIN REFERENCE NO. : 1742021 LAST UPDATED : 199701 DATA ITEMS CITED : 28 MOLECULAR FORMULA : C3-H8-N2-O MOLECULAR WEIGHT : 88.13 WISWESSER LINE NOTATION : ONN2&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 90 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 600 mg/kg/15W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : 108 mg/kg/20W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 420 mg/kg/71W-C TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Reproductive - Tumorigenic effects - other reproductive system tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2250 mg/kg/30W-C TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 360 mg/kg/30W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 90 mg/kg/30W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 600 mg/kg/15W-C TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 72 mg/kg/30W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 700 mg/kg/30W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : 360 mg/kg/20W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors TYPE OF TEST : Specific locus test TYPE OF TEST : DNA damage MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 1 umol/L REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,406,1980 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 17,221,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 17,221,1978 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FRANCE;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993

安全

• 危害码 (欧洲): T+
• 危险品运输编码: UN 2810
• 包装等级: III
• 危险类别: 6.1(b)
• 海关编码: 2928000090

合成路线

118843-34-8 ~96% 10595-95-6

文献：Synthetic Communications, , vol. 19, # 7,8 p. 1147 - 1156

7181-48-8 ~% 10595-95-6 100-52-7

文献：Journal of Organic Chemistry, , vol. 47, # 25 p. 4833 - 4841

60890-81-5 ~% 10595-95-6

文献：Journal of the Chemical Society, , p. 1312

62-75-9 74-88-4 ~% 10595-95-6

文献：Chemische Berichte, , vol. 108, p. 1293 - 1320

96724-44-6 74-88-4 ~% 10595-95-6 57497-34-4

文献：Journal of Organic Chemistry, , vol. 55, # 26 p. 6373 - 6374

海关

海关编码	2928000090
中文概述	2928000090 其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%