151103-09-2

• 常用中文名：4-(二氟甲氧基)-3-(环丙基甲氧基)苯甲醛
• 常用英文名：4-(difluoromethoxy)-3-(cyclopropylmethoxy)-benzaldethyde
• CAS号：151103-09-2
• 分子式：C₁₂H₁₂F₂O₃
• 分子量：242.219
• 发布时间：2018-12-28 07:50:26
• 更新时间：2024-01-04 10:09:08

名称

• 中文名: 4-(二氟甲氧基)-3-(环丙基甲氧基)苯甲醛
• 英文名: 3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzaldehyde
• 中文别名: 罗氟司特-im D; 3-(环丙甲氧基)-4-(二氟甲氧基)苯甲醛
• 英文别名: Benzaldehyde, 3-(cyclopropylmethoxy)-4-(difluoromethoxy)-; 4-(Difluoromethoxy)-3-(cyclopropylmethoxy)benzaldehyde; 3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzaldehyde; 4-(difluoromethoxy)-3-(cyclopropylmethoxy)-benzaldethyde; Roflumilast Impurity 9

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 331.3±37.0 °C at 760 mmHg
• 分子式: C₁₂H₁₂F₂O₃
• 分子量: 242.219
• 闪点: 149.1±21.4 °C
• 精确质量: 242.075455
• PSA: 35.53000
• LogP: 2.69
• 外观性状: 无色至淡黄色至黄棕色液体
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.529
• 储存条件: 室温，干燥

安全

• 危害码 (欧洲): Xn
• 海关编码: 2913000090

合成路线

7051-34-5 151103-08-1 ~96% 151103-09-2

文献：INTERQUIM, S.A.; SALAET FERRE, Josep; MARQUILLAS OLONDRIZ, Francisco Patent: WO2014/60464 A1, 2014 ; Location in patent: Page/Page column 15 ;

139-85-5 ~% 151103-09-2

文献：Armani, Elisabetta; Amari, Gabriele; Rizzi, Andrea; Fanti, Renato De; Ghidini, Eleonora; Capaldi, Carmelida; Carzaniga, Laura; Caruso, Paola; Guala, Matilde; Peretto, Ilaria; La Porta, Elena; Bolzoni, Pier T.; Facchinetti, Fabrizio; Carnini, Chiara; Moretto, Nadia; Patacchini, Riccardo; Bassani, Franco; Cenacchi, Valentina; Volta, Roberta; Amadei, Francesco; Capacchi, Silvia; Delcanale, Maurizio; Puccini, Paola; Catinella, Silvia; Civelli, Maurizio; Villetti, Gino Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 793 - 816

海关

海关编码	2913000090
中文概述	2913000090 品目2912所列产品的其他衍生物〔指卤化,磺化,硝化或亚硝化的衍生物〕. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%