31140-42-8

• 常用中文名：3-Boc-氨基-2,6-二氧代哌啶
• 常用英文名：3-Boc-amino-2,6-dioxopiperidine
• CAS号：31140-42-8
• 分子式：C₁₀H₁₆N₂O₄
• 分子量：228.245
• 发布时间：2019-01-02 13:00:27
• 更新时间：2026-07-14 15:53:02

名称

• 中文名: 3-N-叔丁氧羰基氨基-2,6-二氧代哌啶
• 英文名: 3-boc-amino-2,6-dioxopiperidine
• 中文别名: 3-(BOC-氨基)哌啶-2,6-二酮; 3-BOC-氨基-2,6-哌啶酮; 3-Boc-氨基-2,6-二氧哌啶; 泊马度胺、来那度胺中一; N-(2,6-二氧代哌啶-3-基)氨基甲酸叔丁酯(泊马度胺杂质; 来那度胺杂质29; 3-BOC-氨基-2,6-二氧代哌啶; 3-BOC-氨基-2,6-二氧哌啶; 叔-丁基2,6-二氧代哌啶-3-基氨基甲酸酯; N-(2,6-二氧代哌啶-3-基)氨基甲酸叔丁酯; 3-N-叔丁氧羰基氨基-2,6-二氧代哌啶(泊马度胺中间体)
• 英文别名: TERT-BUTYL 2,6-DIOXOPIPERIDIN-3-YLCBAMATE; 1,1-Dimethylethyl N-(2,6-dioxo-3-piperidinyl)cbamate; tert-Butyl (2,6-dioxopiperidin-3-yl)carbamate; 3-(Boc-amino)piperidine-2,6-dione; 2,6-Dioxo-3-piperidinecbamic acid tert-butyl ester; 2,6-Dioxo-3-piperidinecarbamic acid tert-butyl ester; tert-Butyl N-(2,6-dioxopiperidin-3-yl)cbamate; 3-N-tert butoxycbonylamino-2,6-dioxo piperidine; tert-Butyl N-(2,6-dioxopiperidin-3-yl)cbamate (Pomalidomide Impurity); Carbamic acid, N-(2,6-dioxo-3-piperidinyl)-, 1,1-dimethylethyl ester; Pomalidomide/lenalidomide INT I; CbaMic acid, (2,6-dioxo-3-piperidinyl)-, 1,1-diMethylethyl ester; 1-amino-2,6-dioxo-3-piperidinecboxylic acid tert-butyl ester; 2-Methyl-2-propanyl (2,6-dioxo-3-piperidinyl)carbamate; 3-BOC-AMINO-2,6-DIOXOPIPERIDINE; tert-butyl 2,6-dioxopiperidin-3-yl carbamate; tert-butyl N-(2,6-dioxo-3-piperidyl)cbamate; Cbamic acid, N-(2,6-dioxo-3-piperidinyl)-, 1,1-dimethylethyl ester; (Lenalidomide Intermediate)

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 423.0±34.0 °C at 760 mmHg
• 分子式: C₁₀H₁₆N₂O₄
• 分子量: 228.245
• 闪点: 209.6±25.7 °C
• 精确质量: 228.111008
• PSA: 84.50000
• LogP: 0.73
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.500
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2925190090

合成路线

13726-85-7 ~76% 31140-42-8

文献：Stewart, Scott G.; Braun, Carlos J.; Ng, Sze-Ling; Polomska, Marta E.; Karimi, Mahdad; Abraham, Lawrence J. Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 2 p. 650 - 662

85535-45-1 ~91% 31140-42-8

文献：Nakamura, Takanori; Noguchi, Tomomi; Kobayashi, Hisayoshi; Miyachi, Hiroyuki; Hashimoto, Yuichi Chemical and Pharmaceutical Bulletin, 2006 , vol. 54, # 12 p. 1709 - 1714 Title/Abstract Full Text View citing articles Show Details Nakamura, Takanori; Noguchi, Tomomi; Miyachi, Hiroyuki; Hashimoto, Yuichi Chemical and Pharmaceutical Bulletin, 2007 , vol. 55, # 4 p. 651 - 654

120341-33-5 ~94% 31140-42-8

文献：Contino-Pepin, Christiane; Parat, Audrey; Perino, Sandrine; Lenoir, Christine; Vidal, Michel; Galons, Herve; Karlik, Stephen; Pucci, Bernard Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 3 p. 878 - 881

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海关

海关编码	2925190090
中文概述	2925190090 其他酰亚胺及其衍生物盐. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%